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FB:Myd88
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Myd88 ( synonyms: CG2078, DMMYD88, DmMyD88, DmMyd88, EP(2)2535, Kra, LD20892, MYD88, MyD88, Myd88F, dMyD88, dMyd88, kra, krapfen, myd88 ) | |
| Protein Name(s) | Myd88, | |
| External Links | ||
| FB | FBgn0033402 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002781 |
antifungal peptide production |
FB:FBrf0141679 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0002804 |
positive regulation of antifungal peptide production |
FB:FBrf0141679 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0005121 |
Toll binding |
FB:FBrf0141679 |
IPI: Inferred from Physical Interaction |
FB:FBgn0262473 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0139798 |
IPI: Inferred from Physical Interaction |
FB:FBgn0038928 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0193565 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001990 |
F |
From FB |
||
| GO:0005622 |
intracellular |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006955 |
immune response |
FB:FBrf0159908 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006965 |
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria |
FB:FBrf0151181 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007165 |
signal transduction |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0141679 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003882 |
P |
From FB |
||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0141679 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010441 |
P |
From FB |
||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0174342 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008063 |
Toll signaling pathway |
FB:FBrf0179043 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009620 |
response to fungus |
FB:FBrf0159908 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009953 |
dorsal/ventral pattern formation |
FB:FBrf0155743 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009953 |
dorsal/ventral pattern formation |
FB:FBrf0155935 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0019732 |
antifungal humoral response |
FB:FBrf0151181 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045087 |
innate immune response |
FB:FBrf0188361 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0050830 |
defense response to Gram-positive bacterium |
FB:FBrf0141679 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050832 |
defense response to fungus |
FB:FBrf0141679 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Tauszig-Delamasure S et al. (2002) Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections. Nat Immunol 3: 91-7 PubMed GONUTS page
- ↑ Horng T & Medzhitov R (2001) Drosophila MyD88 is an adapter in the Toll signaling pathway. Proc Natl Acad Sci U S A 98: 12654-8 PubMed GONUTS page
- ↑ Chen LY et al. (2006) Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo. Curr Biol 16: 1183-93 PubMed GONUTS page
- ↑ 4.0 4.1 Janssens S & Beyaert R (2002) A universal role for MyD88 in TLR/IL-1R-mediated signaling. Trends Biochem Sci 27: 474-82 PubMed GONUTS page
- ↑ Brennan CA & Anderson KV (2004) Drosophila: the genetics of innate immune recognition and response. Annu Rev Immunol 22: 457-83 PubMed GONUTS page
- ↑ Leclerc V & Reichhart JM (2004) The immune response of Drosophila melanogaster. Immunol Rev 198: 59-71 PubMed GONUTS page
- ↑ Kambris Z et al. (2003) DmMyD88 controls dorsoventral patterning of the Drosophila embryo. EMBO Rep 4: 64-9 PubMed GONUTS page
- ↑ Charatsi I et al. (2003) Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo. Mech Dev 120: 219-26 PubMed GONUTS page
- ↑ Kwiatkowski DP (2005) The complexity of genetic variation in a simple immune system. Trends Genet 21: 197-9 PubMed GONUTS page
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