Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:Myb

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Myb ( synonyms: CG9045, D-myb, DMyb, Dm Myb, Dm myb, Dm-Myb, Dm-myb, DmMYB, DmMyb, Dmyb, MYB, c-Myb, c-myb, dMyb, dmMYB, dmyb, l(1)XVI, myb, p85 )
Protein Name(s) Myb oncogene-like,
External Links
FB FBgn0002914

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000278

mitotic cell cycle

FB:FBrf0202994
PMID:18316477[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0000910

cytokinesis

FB:FBrf0149163
PMID:12032301[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003677

DNA binding

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P01103

F

From FB

GO:0003677

DNA binding

FB:FBrf0123360

NAS: Non-traceable Author Statement

F

From FB

GO:0003677

DNA binding

FB:FBrf0155469
PMID:12490953[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0167269
PMID:14616073[4]

TAS: Traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P01103

C

From FB

GO:0005634

nucleus

FB:FBrf0123360

NAS: Non-traceable Author Statement

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0200827
PMID:17403774[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005719

nuclear euchromatin

FB:FBrf0201787
PMID:17450131[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0005719

nuclear euchromatin

FB:FBrf0205473
PMID:18424081[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P01103

P

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0144853
PMID:11847115[8]

IDA: Inferred from Direct Assay

P

From FB

GO:0007030

Golgi organization

FB:FBrf0215221
PMID:21847093[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007049

cell cycle

FB:FBrf0144853
PMID:11847115[8]

IGI: Inferred from Genetic Interaction

FB:FBgn0000405

P

From FB

GO:0007049

cell cycle

FB:FBrf0144853
PMID:11847115[8]

IGI: Inferred from Genetic Interaction

FB:FBgn0003525

P

From FB

GO:0007049

cell cycle

FB:FBrf0144853
PMID:11847115[8]

IGI: Inferred from Genetic Interaction

FB:FBgn0004106

P

From FB

GO:0007049

cell cycle

FB:FBrf0144853
PMID:11847115[8]

IGI: Inferred from Genetic Interaction

FB:FBgn0261617

P

From FB

GO:0007049

cell cycle

FB:FBrf0144853
PMID:11847115[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007051

spindle organization

FB:FBrf0149163
PMID:12032301[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007052

mitotic spindle organization

FB:FBrf0200397
PMID:17412918[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007067

mitosis

FB:FBrf0149163
PMID:12032301[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007067

mitosis

FB:FBrf0200397
PMID:17412918[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007088

regulation of mitosis

FB:FBrf0160535
PMID:12834870[11]

IGI: Inferred from Genetic Interaction

FB:FBgn0261617

P

From FB

GO:0007088

regulation of mitosis

FB:FBrf0160535
PMID:12834870[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007088

regulation of mitosis

FB:FBrf0202994
PMID:18316477[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0007098

centrosome cycle

FB:FBrf0144834
PMID:11807028[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007099

centriole replication

FB:FBrf0206048
PMID:18798690[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007307

eggshell chorion gene amplification

FB:FBrf0155469
PMID:12490953[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007307

eggshell chorion gene amplification

FB:FBrf0167269
PMID:14616073[4]

TAS: Traceable Author Statement

P

From FB

GO:0008283

cell proliferation

FB:FBrf0144834
PMID:11807028[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008284

positive regulation of cell proliferation

FB:FBrf0215221
PMID:21847093[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030261

chromosome condensation

FB:FBrf0201787
PMID:17450131[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031523

Myb complex

FB:FBrf0155469
PMID:12490953[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0031523

Myb complex

FB:FBrf0180022
PMID:15479636[14]

IDA: Inferred from Direct Assay

C

From FB

GO:0031523

Myb complex

FB:FBrf0180259
PMID:15545624[15]

IDA: Inferred from Direct Assay

C

From FB

GO:0045792

negative regulation of cell size

FB:FBrf0215221
PMID:21847093[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045931

positive regulation of mitotic cell cycle

FB:FBrf0215221
PMID:21847093[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051297

centrosome organization

FB:FBrf0201458
PMID:17412918[10]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Wen H et al. (2008) Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex. Genes Dev 22: 601-14 PubMed GONUTS page
  2. 2.0 2.1 2.2 Manak JR et al. (2002) Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability. Proc Natl Acad Sci U S A 99: 7438-43 PubMed GONUTS page
  3. 3.0 3.1 3.2 Beall EL et al. (2002) Role for a Drosophila Myb-containing protein complex in site-specific DNA replication. Nature 420: 833-7 PubMed GONUTS page
  4. 4.0 4.1 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
  5. Beall EL et al. (2007) Discovery of tMAC: a Drosophila testis-specific meiotic arrest complex paralogous to Myb-Muv B. Genes Dev 21: 904-19 PubMed GONUTS page
  6. 6.0 6.1 Manak JR et al. (2007) Loss of Drosophila Myb interrupts the progression of chromosome condensation. Nat Cell Biol 9: 581-7 PubMed GONUTS page
  7. Scaria GS et al. (2008) Two components of the Myb complex, DMyb and Mip130, are specifically associated with euchromatin and degraded during prometaphase throughout development. Mech Dev 125: 646-61 PubMed GONUTS page
  8. 8.0 8.1 8.2 8.3 8.4 8.5 Okada M et al. (2002) Myb controls G(2)/M progression by inducing cyclin B expression in the Drosophila eye imaginal disc. EMBO J 21: 675-84 PubMed GONUTS page
  9. 9.0 9.1 9.2 9.3 Zacharogianni M et al. (2011) ERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane association. EMBO J 30: 3684-700 PubMed GONUTS page
  10. 10.0 10.1 10.2 Goshima G et al. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-21 PubMed GONUTS page
  11. 11.0 11.1 Fung SM et al. (2003) MYB and CBP: physiological relevance of a biochemical interaction. Mech Dev 120: 711-20 PubMed GONUTS page
  12. 12.0 12.1 Fung SM et al. (2002) Mutations in Drosophila myb lead to centrosome amplification and genomic instability. Development 129: 347-59 PubMed GONUTS page
  13. Dobbelaere J et al. (2008) A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. PLoS Biol 6: e224 PubMed GONUTS page
  14. Korenjak M et al. (2004) Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Cell 119: 181-93 PubMed GONUTS page
  15. Lewis PW et al. (2004) Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex. Genes Dev 18: 2929-40 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox