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FB:Mtl

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Mtl ( synonyms: 5588, CG5588, MTL, Mt1/Mig2-like, Mtl(Rac-like), Rac, Rac GTPase, Rac-like, dMig-2, mtl )
Protein Name(s) Mig-2-like,
External Links
FB FBgn0039532

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002009

morphogenesis of an epithelium

FB:FBrf0151280
PMID:12147138[1]

TAS: Traceable Author Statement

P

From FB

GO:0003924

GTPase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0004219

F

From FB

GO:0003924

GTPase activity

FB:FBrf0126091

NAS: Non-traceable Author Statement

F

From FB

GO:0003924

GTPase activity

FB:FBrf0128071

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0003924

GTPase activity

FB:FBrf0128589
PMID:10847683[2]

ISS: Inferred from Sequence or Structural Similarity

WP:CE18544

F

From FB

GO:0005525

GTP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001806
InterPro:IPR003578
InterPro:IPR005225

F

From FB

GO:0005622

intracellular

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR003578

C

From FB

GO:0006974

response to DNA damage stimulus

FB:FBrf0208272
PMID:19543366[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007254

JNK cascade

FB:FBrf0187401
PMID:15936337[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007264

small GTPase mediated signal transduction

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001806
InterPro:IPR003578

P

From FB

GO:0007390

germ-band shortening

FB:FBrf0187401
PMID:15936337[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007391

dorsal closure

FB:FBrf0151280
PMID:12147138[1]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0187401
PMID:15936337[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007394

dorsal closure, elongation of leading edge cells

FB:FBrf0187401
PMID:15936337[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007435

salivary gland morphogenesis

FB:FBrf0190152
PMID:16412417[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008258

head involution

FB:FBrf0187401
PMID:15936337[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030032

lamellipodium assembly

FB:FBrf0187401
PMID:15936337[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035099

hemocyte migration

FB:FBrf0184064
PMID:15699212[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051017

actin filament bundle assembly

FB:FBrf0187401
PMID:15936337[4]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
  2. Newsome TP et al. (2000) Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila. Cell 101: 283-94 PubMed GONUTS page
  3. Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Woolner S et al. (2005) The small GTPase Rac plays multiple roles in epithelial sheet fusion--dynamic studies of Drosophila dorsal closure. Dev Biol 282: 163-73 PubMed GONUTS page
  5. Pirraglia C et al. (2006) Rac function in epithelial tube morphogenesis. Dev Biol 290: 435-46 PubMed GONUTS page
  6. Stramer B et al. (2005) Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration. J Cell Biol 168: 567-73 PubMed GONUTS page
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