GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Mt2
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Mt2 ( synonyms: CG10692, DNA methyltransferase 2, DNA(5-cytosine) methyltransferase, DNMT, DNMT2, DmMT2, Dnmt, Dnmt2, cytosine-5 methyltransferase, dDNMT, dDNMT2, dDnmt2, dnmt2, nmt2 ) | |
| Protein Name(s) | Methyltransferase 2, | |
| External Links | ||
| FB | FBgn0028707 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000723 |
telomere maintenance |
FB:FBrf0208049 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0003886 |
DNA (cytosine-5-)-methyltransferase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:AF012129 |
F |
From FB |
||
| GO:0003886 |
DNA (cytosine-5-)-methyltransferase activity |
FB:FBrf0116296 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003886 |
DNA (cytosine-5-)-methyltransferase activity |
FB:FBrf0123223 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003886 |
DNA (cytosine-5-)-methyltransferase activity |
FB:FBrf0173168 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0162085 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006306 |
DNA methylation |
FB:FBrf0123223 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:1274787 |
P |
From FB |
||
| GO:0006306 |
DNA methylation |
FB:FBrf0154293 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006306 |
DNA methylation |
FB:FBrf0173168 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006979 |
response to oxidative stress |
FB:FBrf0211424 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008168 |
methyltransferase activity |
FB:FBrf0111919 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:1274787 |
F |
From FB |
||
| GO:0008175 |
tRNA methyltransferase activity |
FB:FBrf0211424 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0187791 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009408 |
response to heat |
FB:FBrf0211424 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010494 |
cytoplasmic stress granule |
FB:FBrf0211424 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016458 |
gene silencing |
FB:FBrf0208049 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030488 |
tRNA methylation |
FB:FBrf0190608 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030488 |
tRNA methylation |
FB:FBrf0211424 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043045 |
DNA methylation involved in embryo development |
FB:FBrf0162085 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043045 |
DNA methylation involved in embryo development |
FB:FBrf0208049 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0044026 |
DNA hypermethylation |
FB:FBrf0210815 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
colocalizes_with |
GO:0000790 |
nuclear chromatin |
FB:FBrf0145717 |
NAS: Non-traceable Author Statement |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Phalke S et al. (2009) Retrotransposon silencing and telomere integrity in somatic cells of Drosophila depends on the cytosine-5 methyltransferase DNMT2. Nat Genet 41: 696-702 PubMed GONUTS page
- ↑ 2.0 2.1 Tweedie S et al. (1999) Vestiges of a DNA methylation system in Drosophila melanogaster? Nat Genet 23: 389-90 PubMed GONUTS page
- ↑ 3.0 3.1 Tang LY et al. (2003) The eukaryotic DNMT2 genes encode a new class of cytosine-5 DNA methyltransferases. J Biol Chem 278: 33613-6 PubMed GONUTS page
- ↑ 4.0 4.1 Kunert N et al. (2003) A Dnmt2-like protein mediates DNA methylation in Drosophila. Development 130: 5083-90 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Schaefer M et al. (2010) RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage. Genes Dev 24: 1590-5 PubMed GONUTS page
- ↑ Hung MS et al. (1999) Drosophila proteins related to vertebrate DNA (5-cytosine) methyltransferases. Proc Natl Acad Sci U S A 96: 11940-5 PubMed GONUTS page
- ↑ Lin MJ et al. (2005) DNA methyltransferase gene dDnmt2 and longevity of Drosophila. J Biol Chem 280: 861-4 PubMed GONUTS page
- ↑ Goll MG et al. (2006) Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science 311: 395-8 PubMed GONUTS page
- ↑ Gou D et al. (2010) SETDB1 is involved in postembryonic DNA methylation and gene silencing in Drosophila. PLoS One 5: e10581 PubMed GONUTS page
cd |
d cont.gmnr |
r cont.t |
