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FB:Moe
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Moe ( synonyms: CG10701, D17, DMoesin, Dmoe, Dmoesin, EMR1, ERM, Emr1, Ezrin-Radixin-Moesin, Ezrin-moesin-radixin-1, anon-WO03040301.155, anon-WO03040301.157, anon-WO03040301.159, anon-WO03040301.161, dMoe, dMoesin, l(1)G0067, l(1)G0323, l(1)G0404, l(1)G0415, moe, moesin, moesin/ezrin/radixin homolog mRNA ) | |
| Protein Name(s) | Moesin, | |
| External Links | ||
| FB | FBgn0011661 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002009 |
morphogenesis of an epithelium |
FB:FBrf0179391 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0124043 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0167430 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0088536 |
IPI: Inferred from Physical Interaction |
FB:FBgn0086384 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0208602 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0179391 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0208602 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0088536 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0091300 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0179391 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0192194 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005912 |
adherens junction |
FB:FBrf0124043 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005938 |
cell cortex |
FB:FBrf0208602 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007010 |
cytoskeleton organization |
FB:FBrf0179391 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007314 |
oocyte anterior/posterior axis specification |
FB:FBrf0152248 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007315 |
pole plasm assembly |
FB:FBrf0179391 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007318 |
pole plasm protein localization |
FB:FBrf0179391 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007368 |
determination of left/right symmetry |
FB:FBrf0205051 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008092 |
cytoskeletal protein binding |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0008092 |
cytoskeletal protein binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000798 |
F |
From FB |
||
| GO:0008104 |
protein localization |
FB:FBrf0179391 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009952 |
anterior/posterior pattern specification |
FB:FBrf0179391 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016057 |
regulation of membrane potential in photoreceptor cell |
FB:FBrf0190927 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0016336 |
establishment or maintenance of polarity of larval imaginal disc epithelium |
FB:FBrf0155521 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0019898 |
extrinsic to membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000798 |
C |
From FB |
||
| GO:0030029 |
actin filament-based process |
FB:FBrf0155468 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0030036 |
actin cytoskeleton organization |
FB:FBrf0152248 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0032956 |
regulation of actin cytoskeleton organization |
FB:FBrf0202814 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035003 |
subapical complex |
FB:FBrf0155581 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0035088 |
establishment or maintenance of apical/basal cell polarity |
FB:FBrf0179391 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042048 |
olfactory behavior |
FB:FBrf0192106 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042052 |
rhabdomere development |
FB:FBrf0167536 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042462 |
eye photoreceptor cell development |
FB:FBrf0179391 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045197 |
establishment or maintenance of epithelial cell apical/basal polarity |
FB:FBrf0155521 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045313 |
rhabdomere membrane biogenesis |
FB:FBrf0167536 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
NOT |
GO:0045169 |
fusome |
FB:FBrf0091300 |
IDA: Inferred from Direct Assay |
C |
From FB |
||
|
colocalizes_with |
GO:0005819 |
spindle |
FB:FBrf0208602 |
IDA: Inferred from Direct Assay |
C |
From FB |
||
|
colocalizes_with |
GO:0005884 |
actin filament |
FB:FBrf0208602 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Polesello C & Payre F (2004) Small is beautiful: what flies tell us about ERM protein function in development. Trends Cell Biol 14: 294-302 PubMed GONUTS page
- ↑ Gibson MC & Perrimon N (2003) Apicobasal polarization: epithelial form and function. Curr Opin Cell Biol 15: 747-52 PubMed GONUTS page
- ↑ 3.0 3.1 McCartney BM & Fehon RG (1996) Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin. J Cell Biol 133: 843-52 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Vilmos P et al. (2009) Live imaging reveals that the Drosophila actin-binding ERM protein, moesin, co-localizes with the mitotic spindle. Eur J Cell Biol 88: 609-19 PubMed GONUTS page
- ↑ 5.0 5.1 de Cuevas M et al. (1996) alpha-spectrin is required for germline cell division and differentiation in the Drosophila ovary. Development 122: 3959-68 PubMed GONUTS page
- ↑ Verdier V et al. (2006) Drosophila Rho-kinase (DRok) is required for tissue morphogenesis in diverse compartments of the egg chamber during oogenesis. Dev Biol 297: 417-32 PubMed GONUTS page
- ↑ 7.0 7.1 Polesello C et al. (2002) Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis. Nat Cell Biol 4: 782-9 PubMed GONUTS page
- ↑ Taniguchi K et al. (2007) Roles of type I myosins in Drosophila handedness. Fly (Austin) 1: 287-90 PubMed GONUTS page
- ↑ Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
- ↑ Chorna-Ornan I et al. (2005) Light-regulated interaction of Dmoesin with TRP and TRPL channels is required for maintenance of photoreceptors. J Cell Biol 171: 143-52 PubMed GONUTS page
- ↑ 11.0 11.1 Speck O et al. (2003) Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity. Nature 421: 83-7 PubMed GONUTS page
- ↑ Baum B (2002) Drosophila oogenesis: generating an axis of polarity. Curr Biol 12: R835-7 PubMed GONUTS page
- ↑ Kunda P et al. (2008) Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis. Curr Biol 18: 91-101 PubMed GONUTS page
- ↑ Médina E et al. (2002) Role of the Crumbs complex in the regulation of junction formation in Drosophila and mammalian epithelial cells. Biol Cell 94: 305-13 PubMed GONUTS page
- ↑ Sambandan D et al. (2006) Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics 174: 1349-63 PubMed GONUTS page
- ↑ 16.0 16.1 Karagiosis SA & Ready DF (2004) Moesin contributes an essential structural role in Drosophila photoreceptor morphogenesis. Development 131: 725-32 PubMed GONUTS page
