![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Mkp3
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Mkp3 ( synonyms: CG14080, CG14081, DMKP-3, Dmkp3, Drosophila MKP-3, MAP Kinase Phosphatase 3, MAPK phosphatase 3, MAPK phosphatase-3, MKP-3-like, MKP-like, MKP3, Map kinase phosphatase 3, mkp-3, mkp3 ) | |
| Protein Name(s) | Mitogen-activated protein kinase phosphatase 3, | |
| External Links | ||
| FB | FBgn0036844 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002385 |
mucosal immune response |
FB:FBrf0208708 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004725 |
protein tyrosine phosphatase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0141384 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0141384 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0007428 |
primary branching, open tracheal system |
FB:FBrf0192922 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007474 |
imaginal disc-derived wing vein specification |
FB:FBrf0183898 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008138 |
protein tyrosine/serine/threonine phosphatase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:U43223 |
F |
From FB |
||
| GO:0008138 |
protein tyrosine/serine/threonine phosphatase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0016337 |
cell-cell adhesion |
FB:FBrf0192922 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016791 |
phosphatase activity |
FB:FBrf0141384 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0017017 |
MAP kinase tyrosine/serine/threonine phosphatase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:U43223 |
F |
From FB |
||
| GO:0035160 |
maintenance of epithelial integrity, open tracheal system |
FB:FBrf0192922 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042127 |
regulation of cell proliferation |
FB:FBrf0206542 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0043409 |
negative regulation of MAPK cascade |
FB:FBrf0183898 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ha EM et al. (2009) Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut. Nat Immunol 10: 949-57 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Kim SH et al. (2002) Isolation and characterization of a Drosophila homologue of mitogen-activated protein kinase phosphatase-3 which has a high substrate specificity towards extracellular-signal-regulated kinase. Biochem J 361: 143-51 PubMed GONUTS page
- ↑ 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Cela C & Llimargas M (2006) Egfr is essential for maintaining epithelial integrity during tracheal remodelling in Drosophila. Development 133: 3115-25 PubMed GONUTS page
- ↑ 5.0 5.1 Gómez AR et al. (2005) Conserved cross-interactions in Drosophila and Xenopus between Ras/MAPK signaling and the dual-specificity phosphatase MKP3. Dev Dyn 232: 695-708 PubMed GONUTS page
- ↑ Jiang H & Edgar BA (2009) EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development 136: 483-93 PubMed GONUTS page