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FB:Mkk4
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Mkk4 ( synonyms: 142758_at, CG9738, CT27508, D-MKK4, DMKK4, Drosophila MAP kinase kinase 4, JNK kinase 2, JNKK2, MAPKK4, MKK4, Map kinase kinase 4, Mpk4, SEK1/MKK4, dMKK4, dMkk4, hep, mkk4 ) | |
| Protein Name(s) | MAP kinase kinase 4, | |
| External Links | ||
| FB | FBgn0024326 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0004702 |
receptor signaling protein serine/threonine kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004708 |
MAP kinase kinase activity |
FB:FBrf0101052 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004708 |
MAP kinase kinase activity |
FB:FBrf0115707 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004708 |
MAP kinase kinase activity |
FB:FBrf0115711 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004708 |
MAP kinase kinase activity |
FB:FBrf0128774 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0101052 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0102625 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0115707 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0115711 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007257 |
activation of JUN kinase activity |
FB:FBrf0102625 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0008545 |
JUN kinase kinase activity |
FB:FBrf0102625 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0008545 |
JUN kinase kinase activity |
FB:FBrf0125504 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0030424 |
axon |
FB:FBrf0209975 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0046330 |
positive regulation of JNK cascade |
FB:FBrf0209260 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010303 |
P |
From FB |
||
| GO:0046330 |
positive regulation of JNK cascade |
FB:FBrf0209260 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0033483 |
P |
From FB |
||
| GO:0046330 |
positive regulation of JNK cascade |
FB:FBrf0209260 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000229 |
P |
From FB |
||
| GO:0048082 |
regulation of adult chitin-containing cuticle pigmentation |
FB:FBrf0215011 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0014006 |
P |
From FB |
||
| GO:0048666 |
neuron development |
FB:FBrf0209975 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Martín-Blanco E (2000) p38 MAPK signalling cascades: ancient roles and new functions. Bioessays 22: 637-45 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Han ZS et al. (1998) A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression. Mol Cell Biol 18: 3527-39 PubMed GONUTS page
- ↑ 4.0 4.1 Rallis A et al. (2010) Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability. Dev Biol 339: 65-77 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Geuking P et al. (2009) A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK. PLoS One 4: e7709 PubMed GONUTS page
- ↑ Sekine Y et al. (2011) p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors. J Cell Sci 124: 3006-16 PubMed GONUTS page
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