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FB:Mi-2

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Mi-2 ( synonyms: 0006/06, 0854/01, CG8103, Dm-Mi-2, MI-2, MI2, Mi 2, Mi2, PHD-containing ATPase, Pha, dMI-2, dMi, dMi-2, dMi2, hb-interacting protein 76, hip76, l(3)01058, l(3)76BDe, l(3)A154.3M3, l(3)L1243, l(3)S000606, l(3)S085401, l(3)j3D4, lethal (3) L1243, pha )
Protein Name(s) No Information Provided.
External Links
FB FBgn0262519

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0207548
PMID:19165147[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0003677

DNA binding

FB:FBrf0147001
PMID:12006495[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003678

DNA helicase activity

FB:FBrf0141274

ISS: Inferred from Sequence or Structural Similarity

EMBL:AF425231

F

From FB

GO:0003682

chromatin binding

FB:FBrf0136575

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P40201

F

From FB

GO:0003682

chromatin binding

FB:FBrf0207548
PMID:19165147[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0004003

ATP-dependent DNA helicase activity

FB:FBrf0111489
PMID:10471706[3]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004386

helicase activity

FB:FBrf0129923
PMID:10908586[4]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0004386

helicase activity

FB:FBrf0136575

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P40201

F

From FB

GO:0005515

protein binding

FB:FBrf0188509
PMID:15695365[5]

IPI: Inferred from Physical Interaction

FB:FBgn0010762

F

From FB

GO:0005515

protein binding

FB:FBrf0207548
PMID:19165147[1]

IPI: Inferred from Physical Interaction

FB:FBgn0035357

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000330
InterPro:IPR001650
InterPro:IPR002464
InterPro:IPR012957
InterPro:IPR012958

F

From FB

GO:0005634

nucleus

FB:FBrf0098626

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0136575

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P40201

C

From FB

GO:0005634

nucleus

FB:FBrf0136575

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0207548
PMID:19165147[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0141519
PMID:11743021[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0212010
PMID:20733004[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0006333

chromatin assembly or disassembly

FB:FBrf0136575

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P40201

P

From FB

GO:0007517

muscle organ development

FB:FBrf0190556
PMID:16547170[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008026

ATP-dependent helicase activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002464

F

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001841
InterPro:IPR001965
InterPro:IPR012957
InterPro:IPR012958

F

From FB

GO:0016581

NuRD complex

FB:FBrf0131031
PMID:10904264[9]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0016581

NuRD complex

FB:FBrf0141519
PMID:11743021[6]

TAS: Traceable Author Statement

C

From FB

GO:0016887

ATPase activity

FB:FBrf0098626

NAS: Non-traceable Author Statement

F

From FB

GO:0016887

ATPase activity

FB:FBrf0147001
PMID:12006495[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0016887

ATPase activity

FB:FBrf0190884
PMID:16223721[10]

IDA: Inferred from Direct Assay

F

From FB

GO:0031491

nucleosome binding

FB:FBrf0190884
PMID:16223721[10]

IDA: Inferred from Direct Assay

F

From FB

GO:0042766

nucleosome mobilization

FB:FBrf0147001
PMID:12006495[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0042766

nucleosome mobilization

FB:FBrf0190884
PMID:16223721[10]

IDA: Inferred from Direct Assay

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[8]

IMP: Inferred from Mutant Phenotype

P

From FB

contributes_to

GO:0070615

nucleosome-dependent ATPase activity

FB:FBrf0207548
PMID:19165147[1]

IDA: Inferred from Direct Assay

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Kunert N et al. (2009) dMec: a novel Mi-2 chromatin remodelling complex involved in transcriptional repression. EMBO J 28: 533-44 PubMed GONUTS page
  2. 2.0 2.1 2.2 Bouazoune K et al. (2002) The dMi-2 chromodomains are DNA binding modules important for ATP-dependent nucleosome mobilization. EMBO J 21: 2430-40 PubMed GONUTS page
  3. Spradling AC et al. (1999) The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. Genetics 153: 135-77 PubMed GONUTS page
  4. Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
  5. Kon C et al. (2005) Developmental roles of the Mi-2/NURD-associated protein p66 in Drosophila. Genetics 169: 2087-100 PubMed GONUTS page
  6. 6.0 6.1 Murawsky CM et al. (2001) Tramtrack69 interacts with the dMi-2 subunit of the Drosophila NuRD chromatin remodelling complex. EMBO Rep 2: 1089-94 PubMed GONUTS page
  7. Reddy BA et al. (2010) Drosophila transcription factor Tramtrack69 binds MEP1 to recruit the chromatin remodeler NuRD. Mol Cell Biol 30: 5234-44 PubMed GONUTS page
  8. 8.0 8.1 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
  9. Ahringer J (2000) NuRD and SIN3 histone deacetylase complexes in development. Trends Genet 16: 351-6 PubMed GONUTS page
  10. 10.0 10.1 10.2 Bouazoune K & Brehm A (2005) dMi-2 chromatin binding and remodeling activities are regulated by dCK2 phosphorylation. J Biol Chem 280: 41912-20 PubMed GONUTS page
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