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FB:Met

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Met ( synonyms: CG1705, DmMet, MET, Methoprene-tolerant protein, Mett, Resistance (1) Juvenile H, Resistance to Juvenile Hormone, Rst(1)JH, bHLHe59, juvenile hormone resistance, met, methoprene tolerant, methoprene-tolerant )
Protein Name(s) Methoprene-tolerant,
External Links
FB FBgn0002723

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

protein_id:BAA33450

F

From FB

GO:0004871

signal transducer activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000014

F

From FB

GO:0005500

juvenile hormone binding

FB:FBrf0105495

NAS: Non-traceable Author Statement

F

From FB

GO:0005500

juvenile hormone binding

FB:FBrf0173271
PMID:14505366[1]

TAS: Traceable Author Statement

F

From FB

GO:0005500

juvenile hormone binding

FB:FBrf0183965
PMID:15720391[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0005634

nucleus

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

protein_id:BAA33450

C

From FB

GO:0005634

nucleus

FB:FBrf0173271
PMID:14505366[1]

TAS: Traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0183965
PMID:15720391[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0173271
PMID:14505366[1]

TAS: Traceable Author Statement

P

From FB

GO:0007165

signal transduction

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000014
InterPro:IPR001610

P

From FB

GO:0008134

transcription factor binding

FB:FBrf0215576
PMID:21832074[3]

IPI: Inferred from Physical Interaction

FB:FBgn0001078

F

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0206889
PMID:18980211[4]

IDA: Inferred from Direct Assay

F

From FB

GO:0043069

negative regulation of programmed cell death

FB:FBrf0216586
PMID:21968404[5]

IGI: Inferred from Genetic Interaction

FB:FBgn0261703

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0183965
PMID:15720391[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0215576
PMID:21832074[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0206889
PMID:18980211[4]

IDA: Inferred from Direct Assay

F

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0215576
PMID:21832074[3]

IPI: Inferred from Physical Interaction

FB:FBgn0001078

F

From FB

GO:0050793

regulation of developmental process

FB:FBrf0180273
PMID:15609573[6]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Wheeler DE & Nijhout HF (2003) A perspective for understanding the modes of juvenile hormone action as a lipid signaling system. Bioessays 25: 994-1001 PubMed GONUTS page
  2. 2.0 2.1 2.2 Miura K et al. (2005) Characterization of the Drosophila Methoprene -tolerant gene product. Juvenile hormone binding and ligand-dependent gene regulation. FEBS J 272: 1169-78 PubMed GONUTS page
  3. 3.0 3.1 3.2 Dubrovsky EB et al. (2011) The Drosophila FTZ-F1 nuclear receptor mediates juvenile hormone activation of E75A gene expression through an intracellular pathway. J Biol Chem 286: 33689-700 PubMed GONUTS page
  4. 4.0 4.1 Bitra K & Palli SR (2009) Interaction of proteins involved in ecdysone and juvenile hormone signal transduction. Arch Insect Biochem Physiol 70: 90-105 PubMed GONUTS page
  5. Abdou MA et al. (2011) Drosophila Met and Gce are partially redundant in transducing juvenile hormone action. Insect Biochem Mol Biol 41: 938-45 PubMed GONUTS page
  6. Flatt T & Kawecki TJ (2004) Pleiotropic effects of methoprene-tolerant (Met), a gene involved in juvenile hormone metabolism, on life history traits in Drosophila melanogaster. Genetica 122: 141-60 PubMed GONUTS page
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