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FB:Mekk1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Mekk1 ( synonyms: CG7717, D-MEKK1, D-Mekk1, DmMEKK1, MEKK, MEKK1, MEKK4, Mekk1/4, dMEKK, dMEKK1, dMEKK4, dMekk1, mekk1, mekk1a, mekk1b ) | |
| Protein Name(s) | Mekk1, | |
| External Links | ||
| FB | FBgn0024329 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000165 |
MAPK cascade |
FB:FBrf0139644 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0001934 |
positive regulation of protein phosphorylation |
FB:FBrf0209636 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0005198 |
P |
From FB |
||
| GO:0002385 |
mucosal immune response |
FB:FBrf0208708 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004702 |
receptor signaling protein serine/threonine kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004709 |
MAP kinase kinase kinase activity |
FB:FBrf0101381 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0004709 |
MAP kinase kinase kinase activity |
FB:FBrf0137634 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004709 |
MAP kinase kinase kinase activity |
FB:FBrf0139644 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0101381 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0139644 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006979 |
response to oxidative stress |
FB:FBrf0190571 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031434 |
mitogen-activated protein kinase kinase binding |
FB:FBrf0139644 |
IPI: Inferred from Physical Interaction |
FB:FBgn0261524 |
F |
From FB |
||
| GO:0031452 |
negative regulation of heterochromatin assembly |
FB:FBrf0214019 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0034605 |
cellular response to heat |
FB:FBrf0139644 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0034605 |
cellular response to heat |
FB:FBrf0214019 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0209636 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0005198 |
P |
From FB |
||
| GO:0045793 |
positive regulation of cell size |
FB:FBrf0209636 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046330 |
positive regulation of JNK cascade |
FB:FBrf0189754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0071243 |
cellular response to arsenic-containing substance |
FB:FBrf0189754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0071276 |
cellular response to cadmium ion |
FB:FBrf0189754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0071475 |
cellular hyperosmotic salinity response |
FB:FBrf0139644 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Inoue H et al. (2001) A Drosophila MAPKKK, D-MEKK1, mediates stress responses through activation of p38 MAPK. EMBO J 20: 5421-30 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Cully M et al. (2010) A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1. Mol Cell Biol 30: 481-95 PubMed GONUTS page
- ↑ Ha EM et al. (2009) Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut. Nat Immunol 10: 949-57 PubMed GONUTS page
- ↑ 4.0 4.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Brun S et al. (2006) The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila. Genes Cells 11: 397-407 PubMed GONUTS page
- ↑ 6.0 6.1 Seong KH et al. (2011) Inheritance of stress-induced, ATF-2-dependent epigenetic change. Cell 145: 1049-61 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Ryabinina OP et al. (2006) D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells. BMC Cell Biol 7: 7 PubMed GONUTS page
