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FB:Mdr65

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Mdr65 ( synonyms: CG10181, MDR65, Mdr65A, P-glycoprotein65-Dm, mdr65 )
Protein Name(s) Multiple drug resistance 65,
External Links
FB FBgn0004513

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001140
InterPro:IPR003439
InterPro:IPR011527
InterPro:IPR017871

F

From FB

GO:0005886

plasma membrane

FB:FBrf0210975

IDA: Inferred from Direct Assay

C

From FB

GO:0005887

integral to plasma membrane

FB:FBrf0124191

NAS: Non-traceable Author Statement

C

From FB

GO:0015238

drug transmembrane transporter activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P08183

F

From FB

GO:0016021

integral to membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001140
InterPro:IPR011527

C

From FB

GO:0031427

response to methotrexate

FB:FBrf0208694
PMID:19545574[1]

IEP: Inferred from Expression Pattern

P

From FB

GO:0042626

ATPase activity, coupled to transmembrane movement of substances

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001140
InterPro:IPR011527

F

From FB

GO:0043190

ATP-binding cassette (ABC) transporter complex

FB:FBrf0207483
PMID:19295159[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0055085

transmembrane transport

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001140
InterPro:IPR011527

P

From FB

GO:0060856

establishment of blood-brain barrier

FB:FBrf0207483
PMID:19295159[2]

IDA: Inferred from Direct Assay

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Chahine S & O'Donnell MJ (2009) Physiological and molecular characterization of methotrexate transport by Malpighian tubules of adult Drosophila melanogaster. J Insect Physiol 55: 927-35 PubMed GONUTS page
  2. 2.0 2.1 Mayer F et al. (2009) Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. J Neurosci 29: 3538-50 PubMed GONUTS page
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