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FB:Mdr65
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Mdr65 ( synonyms: CG10181, MDR65, Mdr65A, P-glycoprotein65-Dm, mdr65 ) | |
| Protein Name(s) | Multiple drug resistance 65, | |
| External Links | ||
| FB | FBgn0004513 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001140 |
F |
From FB |
||
| GO:0005886 |
plasma membrane |
FB:FBrf0210975 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005887 |
integral to plasma membrane |
FB:FBrf0124191 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0015238 |
drug transmembrane transporter activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0031427 |
response to methotrexate |
FB:FBrf0208694 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0042626 |
ATPase activity, coupled to transmembrane movement of substances |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0043190 |
ATP-binding cassette (ABC) transporter complex |
FB:FBrf0207483 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0055085 |
transmembrane transport |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0060856 |
establishment of blood-brain barrier |
FB:FBrf0207483 |
IDA: Inferred from Direct Assay |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Chahine S & O'Donnell MJ (2009) Physiological and molecular characterization of methotrexate transport by Malpighian tubules of adult Drosophila melanogaster. J Insect Physiol 55: 927-35 PubMed GONUTS page
- ↑ 2.0 2.1 Mayer F et al. (2009) Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. J Neurosci 29: 3538-50 PubMed GONUTS page