Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:MTF-1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) MTF-1 ( synonyms: CG3743, Metal-responsive transcription factor 1, anon-WO0118547.411, dMTF-1, metal response element binding transcription factor, metal response element-binding transcription factor-1, metal responsive transcription factor, metal-regulatory transcription factor 1, metal-responsive transcription factor-1, mtf-1 )
Protein Name(s) Metal response element-binding Transcription Factor-1,
External Links
FB FBgn0040305

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000976

transcription regulatory region sequence-specific DNA binding

FB:FBrf0215591
PMID:21870250[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0125652

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0131507

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0192730
PMID:16751183[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0005634

nucleus

FB:FBrf0125652

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0131507

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0192730
PMID:16751183[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0192730
PMID:16751183[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0006351

transcription, DNA-dependent

FB:FBrf0131507

NAS: Non-traceable Author Statement

P

From FB

GO:0006875

cellular metal ion homeostasis

FB:FBrf0155736
PMID:12505988[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR007087
InterPro:IPR015880

F

From FB

GO:0010038

response to metal ion

FB:FBrf0187596
PMID:15833915[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0192730
PMID:16751183[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0046688

response to copper ion

FB:FBrf0179972
PMID:15239669[5]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Atanesyan L et al. (2011) Characterization of MtnE, the fifth metallothionein member in Drosophila. J Biol Inorg Chem 16: 1047-56 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Marr MT 2nd et al. (2006) Coactivator cross-talk specifies transcriptional output. Genes Dev 20: 1458-69 PubMed GONUTS page
  3. Egli D et al. (2003) Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. EMBO J 22: 100-8 PubMed GONUTS page
  4. Selvaraj A et al. (2005) Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes. Genes Dev 19: 891-6 PubMed GONUTS page
  5. Southon A et al. (2004) Copper homoeostasis in Drosophila melanogaster S2 cells. Biochem J 383: 303-9 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox