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FB:MRP
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | MRP ( synonyms: CG6214, Multidrug-resistance protein, dMRP, dMRP/CG6214, multidrug resistance-associated protein, multidrug resistance-like protein 1 ) | |
| Protein Name(s) | Multidrug-Resistance like Protein 1, | |
| External Links | ||
| FB | FBgn0032456 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001140 |
F |
From FB |
||
| GO:0008559 |
xenobiotic-transporting ATPase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:AF022908 |
F |
From FB |
||
| GO:0016021 |
integral to membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0031427 |
response to methotrexate |
FB:FBrf0208694 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0031427 |
response to methotrexate |
FB:FBrf0214072 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0042626 |
ATPase activity, coupled to transmembrane movement of substances |
FB:FBrf0174138 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0043492 |
ATPase activity, coupled to movement of substances |
FB:FBrf0180349 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0055085 |
transmembrane transport |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Chahine S & O'Donnell MJ (2009) Physiological and molecular characterization of methotrexate transport by Malpighian tubules of adult Drosophila melanogaster. J Insect Physiol 55: 927-35 PubMed GONUTS page
- ↑ Chahine S & O'Donnell MJ (2010) Effects of acute or chronic exposure to dietary organic anions on secretion of methotrexate and salicylate by Malpighian tubules of Drosophila melanogaster larvae. Arch Insect Biochem Physiol 73: 128-47 PubMed GONUTS page
- ↑ Tarnay JN et al. (2004) The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family. Insect Mol Biol 13: 539-48 PubMed GONUTS page
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