GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Lam
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Lam ( synonyms: 2459, 74/76, B-type Lamin, B-type lamin, CG6944, D5, DM((O)), Dm, Dm(0), Dm0, Dm1, Dm2, DmLamin, DmO, Dm((0)), Dm((1)), Dm((2)), Dm((mit)), Dm((o)), Dmo, LAM, Lam Dm((0)), Lam(Dm0), LamDm((0)), LamDm((o)), Lam((Dm0)), Lamin B, Lamin D, Lamin D((o)), Lamin Dm0, Lamin DmO, Lamin Dm((0)), Lamin Dmo, Lamin-B, LaminDm, LaminDm0, alpha-Lamin, intermediate filament-like lamina, jf27, l(2)04643, l(2)25Ec, l(2)gdh-7, l(2)gdh7, l(2)jf27, lam, lamDm0, lamDm((0)), lamin, lamin A, lamin B, lamin D((0)), lamin D((m))0, lamin Dm0, lamin Dm((0)), lethal(2)25Ec, misg, misguided, misrouted, n-lamin, nlam, nuclear lamin ) | |
| Protein Name(s) | Lamin, | |
| External Links | ||
| FB | FBgn0002525 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001745 |
compound eye morphogenesis |
FB:FBrf0187393 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005198 |
structural molecule activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0102927 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000927 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0102927 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003022 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0162195 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005635 |
nuclear envelope |
FB:FBrf0190315 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005635 |
nuclear envelope |
FB:FBrf0208977 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005638 |
lamin filament |
FB:FBrf0050196 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005638 |
lamin filament |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:BAA08784 |
C |
From FB |
||
| GO:0005638 |
lamin filament |
FB:FBrf0123468 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005652 |
nuclear lamina |
FB:FBrf0084310 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005652 |
nuclear lamina |
FB:FBrf0207453 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005811 |
lipid particle |
FB:FBrf0192764 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005813 |
centrosome |
FB:FBrf0212030 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005875 |
microtubule associated complex |
FB:FBrf0204649 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006342 |
chromatin silencing |
FB:FBrf0207453 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006998 |
nuclear envelope organization |
FB:FBrf0187393 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007084 |
mitotic nuclear envelope reassembly |
FB:FBrf0056439 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0007084 |
mitotic nuclear envelope reassembly |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:BAA08784 |
P |
From FB |
||
| GO:0007097 |
nuclear migration |
FB:FBrf0167866 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007417 |
central nervous system development |
FB:FBrf0187393 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007430 |
terminal branching, open tracheal system |
FB:FBrf0078541 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007430 |
terminal branching, open tracheal system |
FB:FBrf0138505 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035262 |
gonad morphogenesis |
FB:FBrf0187393 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040003 |
chitin-based cuticle development |
FB:FBrf0187393 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046331 |
lateral inhibition |
FB:FBrf0214518 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048546 |
digestive tract morphogenesis |
FB:FBrf0187393 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051297 |
centrosome organization |
FB:FBrf0212030 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0072686 |
mitotic spindle |
FB:FBrf0212030 |
IDA: Inferred from Direct Assay |
C |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Osouda S et al. (2005) Null mutants of Drosophila B-type lamin Dm(0) show aberrant tissue differentiation rather than obvious nuclear shape distortion or specific defects during cell proliferation. Dev Biol 284: 219-32 PubMed GONUTS page
- ↑ 2.0 2.1 Goldberg M et al. (1998) Interactions among Drosophila nuclear envelope proteins lamin, otefin, and YA. Mol Cell Biol 18: 4315-23 PubMed GONUTS page
- ↑ Furukawa K et al. (2003) Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila. J Cell Sci 116: 3811-23 PubMed GONUTS page
- ↑ Pilot F et al. (2006) Developmental control of nuclear morphogenesis and anchoring by charleston, identified in a functional genomic screen of Drosophila cellularisation. Development 133: 711-23 PubMed GONUTS page
- ↑ Schulze SR et al. (2009) A comparative study of Drosophila and human A-type lamins. PLoS One 4: e7564 PubMed GONUTS page
- ↑ Smith DE & Fisher PA (1989) Interconversion of Drosophila nuclear lamin isoforms during oogenesis, early embryogenesis, and upon entry of cultured cells into mitosis. J Cell Biol 108: 255-65 PubMed GONUTS page
- ↑ Riemer D et al. (1995) Expression of Drosophila lamin C is developmentally regulated: analogies with vertebrate A-type lamins. J Cell Sci 108 ( Pt 10): 3189-98 PubMed GONUTS page
- ↑ 8.0 8.1 Shevelyov YY et al. (2009) The B-type lamin is required for somatic repression of testis-specific gene clusters. Proc Natl Acad Sci U S A 106: 3282-7 PubMed GONUTS page
- ↑ Cermelli S et al. (2006) The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr Biol 16: 1783-95 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Müller H et al. (2010) Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J 29: 3344-57 PubMed GONUTS page
- ↑ Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
- ↑ Ulitzur N et al. (1992) Lamin activity is essential for nuclear envelope assembly in a Drosophila embryo cell-free extract. J Cell Biol 119: 17-25 PubMed GONUTS page
- ↑ Patterson K et al. (2004) The functions of Klarsicht and nuclear lamin in developmentally regulated nuclear migrations of photoreceptor cells in the Drosophila eye. Mol Biol Cell 15: 600-10 PubMed GONUTS page
- ↑ Guillemin K et al. (2001) A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila. Nat Cell Biol 3: 848-51 PubMed GONUTS page
