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FB:Krn
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Krn ( synonyms: CG32179, CG8056, CT19073, Ker, Spitz2, gritz, keren, keren/spitz2, krn, s-krn, skrn, spitz-2, spitz2 ) | |
| Protein Name(s) | Keren, | |
| External Links | ||
| FB | FBgn0052179 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000165 |
MAPK cascade |
FB:FBrf0151286 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0005154 |
epidermal growth factor receptor binding |
FB:FBrf0128028 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005783 |
endoplasmic reticulum |
FB:FBrf0180127 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0126219 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0136839 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007298 |
border follicle cell migration |
FB:FBrf0193922 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008083 |
growth factor activity |
FB:FBrf0148886 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:AAA19941 |
F |
From FB |
||
| GO:0008284 |
positive regulation of cell proliferation |
FB:FBrf0206542 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008284 |
positive regulation of cell proliferation |
FB:FBrf0212840 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016318 |
ommatidial rotation |
FB:FBrf0167498 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042058 |
regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0200846 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003310 |
P |
From FB |
||
| GO:0045741 |
positive regulation of epidermal growth factor-activated receptor activity |
FB:FBrf0151286 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003731 |
P |
From FB |
||
| GO:0045741 |
positive regulation of epidermal growth factor-activated receptor activity |
FB:FBrf0151286 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0200846 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003310 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Reich A & Shilo BZ (2002) Keren, a new ligand of the Drosophila epidermal growth factor receptor, undergoes two modes of cleavage. EMBO J 21: 4287-96 PubMed GONUTS page
- ↑ Schlesinger A et al. (2004) Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Dev Cell 7: 535-45 PubMed GONUTS page
- ↑ McDonald JA et al. (2006) Multiple EGFR ligands participate in guiding migrating border cells. Dev Biol 296: 94-103 PubMed GONUTS page
- ↑ Jiang H & Edgar BA (2009) EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development 136: 483-93 PubMed GONUTS page
- ↑ Buchon N et al. (2010) Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol 8: 152 PubMed GONUTS page
- ↑ Brown KE & Freeman M (2003) Egfr signalling defines a protective function for ommatidial orientation in the Drosophila eye. Development 130: 5401-12 PubMed GONUTS page
- ↑ 7.0 7.1 Brown KE et al. (2007) The EGFR ligands Spitz and Keren act cooperatively in the Drosophila eye. Dev Biol 307: 105-13 PubMed GONUTS page
