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FB:Jra
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Jra ( synonyms: AP-1, AP1, CG2275, Complementation group V, D-Jun, D-jun, D-jun/Jra, DJUN, DJun, Djun, JRA, JUN, Jun, Jun oncogene, Jun related antigen, V, activator protein 1, c-Jun, cJun, d-JRA, d-Jun, d-jun, dAP-1, dJRA, dJUN, dJra, dJun, djun, dm-Jun, jra, jun, l(2)46Ef, l(2)IA109, l(2R)IA109, lethal(2)1A109, lethal(2)IA109 ) | |
| Protein Name(s) | Jun-related antigen, | |
| External Links | ||
| FB | FBgn0001291 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000165 |
MAPK cascade |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000981 |
sequence-specific DNA binding RNA polymerase II transcription factor activity |
FB:FBrf0051862 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0001736 |
establishment of planar polarity |
FB:FBrf0156094 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0123681 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0145123 |
IPI: Inferred from Physical Interaction |
FB:FBgn0044323 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0190553 |
IPI: Inferred from Physical Interaction |
FB:FBgn0028387 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0209550 |
IPI: Inferred from Physical Interaction |
FB:FBgn0028550 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123681 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0137201 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005667 |
transcription factor complex |
FB:FBrf0051862 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001297 |
C |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0137201 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
FB:FBrf0123681 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007254 |
JNK cascade |
FB:FBrf0095018 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000229 |
P |
From FB |
||
| GO:0007254 |
JNK cascade |
FB:FBrf0095018 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010303 |
P |
From FB |
||
| GO:0007254 |
JNK cascade |
FB:FBrf0095018 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010333 |
P |
From FB |
||
| GO:0007254 |
JNK cascade |
FB:FBrf0095018 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007254 |
JNK cascade |
FB:FBrf0110443 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0110443 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0111406 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0149002 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007464 |
R3/R4 cell fate commitment |
FB:FBrf0156094 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007465 |
R7 cell fate commitment |
FB:FBrf0090759 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0123681 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0149002 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0008348 |
negative regulation of antimicrobial humoral response |
FB:FBrf0201134 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0014018 |
P |
From FB |
||
| GO:0008348 |
negative regulation of antimicrobial humoral response |
FB:FBrf0201134 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0051862 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046529 |
imaginal disc fusion, thorax closure |
FB:FBrf0192703 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046843 |
dorsal appendage formation |
FB:FBrf0138279 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046844 |
micropyle formation |
FB:FBrf0138279 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0051862 |
IPI: Inferred from Physical Interaction |
FB:FBgn0001297 |
F |
From FB |
||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0152056 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0051124 |
synaptic growth at neuromuscular junction |
FB:FBrf0207092 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001297 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Perkins KK et al. (1990) The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor. Genes Dev 4: 822-34 PubMed GONUTS page
- ↑ 3.0 3.1 Mlodzik M (2002) Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation? Trends Genet 18: 564-71 PubMed GONUTS page
- ↑ Chen HW et al. (2002) CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila. Mol Cell Biol 22: 1792-803 PubMed GONUTS page
- ↑ Miotto B et al. (2006) Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis. Genes Dev 20: 101-12 PubMed GONUTS page
- ↑ Sekyrova P et al. (2010) Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis. Development 137: 141-50 PubMed GONUTS page
- ↑ 7.0 7.1 Reed BH et al. (2001) Downregulation of Jun kinase signaling in the amnioserosa is essential for dorsal closure of the Drosophila embryo. Curr Biol 11: 1098-108 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Hou XS et al. (1997) Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes Dev 11: 1728-37 PubMed GONUTS page
- ↑ 10.0 10.1 Noselli S & Agnès F (1999) Roles of the JNK signaling pathway in Drosophila morphogenesis. Curr Opin Genet Dev 9: 466-72 PubMed GONUTS page
- ↑ Lamka ML & Lipshitz HD (1999) Role of the amnioserosa in germ band retraction of the Drosophila melanogaster embryo. Dev Biol 214: 102-12 PubMed GONUTS page
- ↑ 12.0 12.1 Van Aelst L & Symons M (2002) Role of Rho family GTPases in epithelial morphogenesis. Genes Dev 16: 1032-54 PubMed GONUTS page
- ↑ Riesgo-Escovar JR et al. (1996) The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. Genes Dev 10: 2759-68 PubMed GONUTS page
- ↑ 14.0 14.1 Kim LK et al. (2007) Down-regulation of NF-kappaB target genes by the AP-1 and STAT complex during the innate immune response in Drosophila. PLoS Biol 5: e238 PubMed GONUTS page
- ↑ Cerrato A et al. (2006) Genetic interactions between Drosophila melanogaster menin and Jun/Fos. Dev Biol 298: 59-70 PubMed GONUTS page
- ↑ 16.0 16.1 Suzanne M et al. (2001) The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle. Dev Biol 237: 282-94 PubMed GONUTS page
- ↑ Fassler J et al. (2002) B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partners. Genome Res 12: 1190-200 PubMed GONUTS page
- ↑ Franciscovich AL et al. (2008) Overexpression screen in Drosophila identifies neuronal roles of GSK-3 beta/shaggy as a regulator of AP-1-dependent developmental plasticity. Genetics 180: 2057-71 PubMed GONUTS page
