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FB:Jafrac2

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Jafrac2 ( synonyms: 1274, CG1274, DPx-4156, DPx4156, JafRac2, Jafrac-2, Peroxiredoxin 4156, Prx4156, jafrac2, thioredoxin peroxidase )
Protein Name(s) thioredoxin peroxidase 2,
External Links
FB FBgn0040308

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004601

peroxidase activity

FB:FBrf0134080

NAS: Non-traceable Author Statement

F

From FB

GO:0005576

extracellular region

FB:FBrf0135114

NAS: Non-traceable Author Statement

C

From FB

GO:0005576

extracellular region

FB:FBrf0139661
PMID:11677042[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006915

apoptotic process

FB:FBrf0167429
PMID:14644196[2]

TAS: Traceable Author Statement

P

From FB

GO:0006917

induction of apoptosis

FB:FBrf0151953
PMID:12356728[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0260635

P

From FB

GO:0006917

induction of apoptosis

FB:FBrf0151953
PMID:12356728[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006917

induction of apoptosis

FB:FBrf0151953
PMID:12356728[3]

IPI: Inferred from Physical Interaction

FB:FBgn0015247

P

From FB

GO:0006917

induction of apoptosis

FB:FBrf0151953
PMID:12356728[3]

IPI: Inferred from Physical Interaction

FB:FBgn0260635

P

From FB

GO:0006974

response to DNA damage stimulus

FB:FBrf0208272
PMID:19543366[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008379

thioredoxin peroxidase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O08807

F

From FB

GO:0008379

thioredoxin peroxidase activity

FB:FBrf0135114

NAS: Non-traceable Author Statement

F

From FB

GO:0008379

thioredoxin peroxidase activity

FB:FBrf0139661
PMID:11677042[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0016209

antioxidant activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O08807

F

From FB

GO:0016209

antioxidant activity

FB:FBrf0134080

NAS: Non-traceable Author Statement

F

From FB

GO:0042744

hydrogen peroxide catabolic process

FB:FBrf0139661
PMID:11677042[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0055114

oxidation-reduction process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000866
InterPro:IPR019479

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Radyuk SN et al. (2001) The peroxiredoxin gene family in Drosophila melanogaster. Free Radic Biol Med 31: 1090-100 PubMed GONUTS page
  2. Bergmann A et al. (2003) Regulators of IAP function: coming to grips with the grim reaper. Curr Opin Cell Biol 15: 717-24 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Tenev T et al. (2002) Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1. EMBO J 21: 5118-29 PubMed GONUTS page
  4. Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
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