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FB:JIL-1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | JIL-1 ( synonyms: 2Ab17, CG6297, IL-1, JIL, JIL-1 histone H3S10 kinase, JIL-1 histone kinase, JIL-1 kinase, JIL1, Jil-1, Jil1, MSK, Su(var)3-1, Su(var)3-103, Su-var(3)1, Su-var(3)103, Suppressor of variegation 3-1, anon-WO0118547.379, mAb2A ) | |
| Protein Name(s) | JIL-1, | |
| External Links | ||
| FB | FBgn0020412 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004672 |
protein kinase activity |
FB:FBrf0110007 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0087473 |
ISS: Inferred from Sequence or Structural Similarity |
protein_id:AAA49959.1 |
F |
From FB |
||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000719 |
F |
From FB |
||
| GO:0005700 |
polytene chromosome |
FB:FBrf0193296 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006325 |
chromatin organization |
FB:FBrf0159904 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006325 |
chromatin organization |
FB:FBrf0202093 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0110007 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000719 |
P |
From FB |
||
| GO:0016321 |
female meiosis chromosome segregation |
FB:FBrf0135802 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016456 |
X chromosome located dosage compensation complex, transcription activating |
FB:FBrf0128809 |
IPI: Inferred from Physical Interaction |
C |
From FB |
|||
| GO:0016456 |
X chromosome located dosage compensation complex, transcription activating |
FB:FBrf0128809 |
IPI: Inferred from Physical Interaction |
C |
From FB |
|||
| GO:0016456 |
X chromosome located dosage compensation complex, transcription activating |
FB:FBrf0128809 |
IPI: Inferred from Physical Interaction |
C |
From FB |
|||
| GO:0016572 |
histone phosphorylation |
FB:FBrf0158834 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016572 |
histone phosphorylation |
FB:FBrf0159904 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016572 |
histone phosphorylation |
FB:FBrf0179061 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0031936 |
negative regulation of chromatin silencing |
FB:FBrf0190333 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035175 |
histone kinase activity (H3-S10 specific) |
FB:FBrf0158834 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0035175 |
histone kinase activity (H3-S10 specific) |
FB:FBrf0179061 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0035175 |
histone kinase activity (H3-S10 specific) |
FB:FBrf0190333 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0167636 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051276 |
chromosome organization |
FB:FBrf0167636 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
colocalizes_with |
GO:0000790 |
nuclear chromatin |
FB:FBrf0136815 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Jin Y et al. (1999) JIL-1: a novel chromosomal tandem kinase implicated in transcriptional regulation in Drosophila. Mol Cell 4: 129-35 PubMed GONUTS page
- ↑ Johansen KM (1996) Dynamic remodeling of nuclear architecture during the cell cycle. J Cell Biochem 60: 289-96 PubMed GONUTS page
- ↑ 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Rath U et al. (2006) The chromodomain protein, Chromator, interacts with JIL-1 kinase and regulates the structure of Drosophila polytene chromosomes. J Cell Sci 119: 2332-41 PubMed GONUTS page
- ↑ 5.0 5.1 Wutz A (2003) RNAs templating chromatin structure for dosage compensation in animals. Bioessays 25: 434-42 PubMed GONUTS page
- ↑ Bao X et al. (2007) Loss-of-function alleles of the JIL-1 histone H3S10 kinase enhance position-effect variegation at pericentric sites in Drosophila heterochromatin. Genetics 176: 1355-8 PubMed GONUTS page
- ↑ Dobie KW et al. (2001) Identification of chromosome inheritance modifiers in Drosophila melanogaster. Genetics 157: 1623-37 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Jin Y et al. (2000) JIL-1, a chromosomal kinase implicated in regulation of chromatin structure, associates with the male specific lethal (MSL) dosage compensation complex. J Cell Biol 149: 1005-10 PubMed GONUTS page
- ↑ 9.0 9.1 Akhtar A (2003) Dosage compensation: an intertwined world of RNA and chromatin remodelling. Curr Opin Genet Dev 13: 161-9 PubMed GONUTS page
- ↑ 10.0 10.1 Nowak SJ & Corces VG (2004) Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation. Trends Genet 20: 214-20 PubMed GONUTS page
- ↑ 11.0 11.1 Zhang W et al. (2006) The JIL-1 histone H3S10 kinase regulates dimethyl H3K9 modifications and heterochromatic spreading in Drosophila. Development 133: 229-35 PubMed GONUTS page
- ↑ 12.0 12.1 Zhang W et al. (2003) Genetic and phenotypic analysis of alleles of the Drosophila chromosomal JIL-1 kinase reveals a functional requirement at multiple developmental stages. Genetics 165: 1341-54 PubMed GONUTS page
- ↑ Wang Y et al. (2001) The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila. Cell 105: 433-43 PubMed GONUTS page
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