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FB:Irbp

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Irbp ( synonyms: CG5247, DmKu70, IRBP, IRBP/Ku70, Ku, Ku70, YPF1, YPF1beta, Yolk protein factor 1b, Ypf1b, dp70, irbp, ku70, p70 )
Protein Name(s) Inverted repeat-binding protein,
External Links
FB FBgn0011774

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000723

telomere maintenance

FB:FBrf0187650
PMID:15781709[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003677

DNA binding

FB:FBrf0068542
PMID:8157678[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003677

DNA binding

FB:FBrf0077259
PMID:7809101[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0003677

DNA binding

FB:FBrf0077259
PMID:7809101[3]

ISS: Inferred from Sequence or Structural Similarity

HGNC:4055

F

From FB

GO:0003677

DNA binding

FB:FBrf0113172

NAS: Non-traceable Author Statement

F

From FB

GO:0003677

DNA binding

FB:FBrf0116483

NAS: Non-traceable Author Statement

F

From FB

GO:0004003

ATP-dependent DNA helicase activity

FB:FBrf0141175

NAS: Non-traceable Author Statement

F

From FB

GO:0004003

ATP-dependent DNA helicase activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR005160
InterPro:IPR006164
InterPro:IPR006165

F

From FB

GO:0004677

DNA-dependent protein kinase activity

FB:FBrf0116483

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0113172

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0141175

NAS: Non-traceable Author Statement

C

From FB

GO:0005958

DNA-dependent protein kinase-DNA ligase 4 complex

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006165

C

From FB

GO:0006303

double-strand break repair via nonhomologous end joining

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR005160
InterPro:IPR006164
InterPro:IPR006165

P

From FB

GO:0043564

Ku70:Ku80 complex

FB:FBrf0068542
PMID:8157678[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0068542
PMID:8157678[2]

IDA: Inferred from Direct Assay

F

From FB

contributes_to

GO:0003677

DNA binding

FB:FBrf0089696
PMID:8663250[4]

IDA: Inferred from Direct Assay

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Melnikova L et al. (2005) The Ku protein complex is involved in length regulation of Drosophila telomeres. Genetics 170: 221-35 PubMed GONUTS page
  2. 2.0 2.1 2.2 Jacoby DB & Wensink PC (1994) Yolk protein factor 1 is a Drosophila homolog of Ku, the DNA-binding subunit of a DNA-dependent protein kinase from humans. J Biol Chem 269: 11484-91 PubMed GONUTS page
  3. 3.0 3.1 Beall EL et al. (1994) A Drosophila protein homologous to the human p70 Ku autoimmune antigen interacts with the P transposable element inverted repeats. Proc Natl Acad Sci U S A 91: 12681-5 PubMed GONUTS page
  4. Jacoby DB & Wensink PC (1996) DNA binding specificities of YPF1, a Drosophila homolog to the DNA binding subunit of human DNA-dependent protein kinase, Ku. J Biol Chem 271: 16827-32 PubMed GONUTS page
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