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FB:Hrs

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Hrs ( synonyms: CG2903, HRS, HRS-2, Hepatocyte growth factor regulated tyrosine kinase, Hepatocyte growth factor-regulated tyrosine kinase substrate, Hepatocyte growth-factor-regulated substrate, Vps27, hepatocyte growth factor-regulated tyrosine kinase substrate, hrs, l(2)23AB5, l(2)23Ad, l(2)23Ad(Hrs), vps27 )
Protein Name(s) Hepatocyte growth factor regulated tyrosine kinase substrate,
External Links
FB FBgn0031450

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

FB:FBrf0126481

NAS: Non-traceable Author Statement

C

From FB

GO:0005768

endosome

FB:FBrf0151490
PMID:12127141[1]

TAS: Traceable Author Statement

C

From FB

GO:0005769

early endosome

FB:FBrf0126481

NAS: Non-traceable Author Statement

C

From FB

GO:0005770

late endosome

FB:FBrf0126481

NAS: Non-traceable Author Statement

C

From FB

GO:0006886

intracellular protein transport

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002014

P

From FB

GO:0006887

exocytosis

FB:FBrf0151490
PMID:12127141[1]

TAS: Traceable Author Statement

P

From FB

GO:0006897

endocytosis

FB:FBrf0159232
PMID:12612640[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0006897

endocytosis

FB:FBrf0190155
PMID:16530179[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007269

neurotransmitter secretion

FB:FBrf0127207
PMID:10798391[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0187407
PMID:16054027[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008021

synaptic vesicle

FB:FBrf0127207
PMID:10798391[4]

NAS: Non-traceable Author Statement

C

From FB

GO:0008293

torso signaling pathway

FB:FBrf0151490
PMID:12127141[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0008333

endosome to lysosome transport

FB:FBrf0126481

TAS: Traceable Author Statement

P

From FB

GO:0016050

vesicle organization

FB:FBrf0159232
PMID:12612640[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0016079

synaptic vesicle exocytosis

FB:FBrf0129948
PMID:10908590[6]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0016082

synaptic vesicle priming

FB:FBrf0127207
PMID:10798391[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0016197

endosome transport

FB:FBrf0151490
PMID:12127141[1]

TAS: Traceable Author Statement

P

From FB

GO:0033565

ESCRT-0 complex

FB:FBrf0210737
PMID:20404143[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

FB:FBrf0151490
PMID:12127141[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0045752

positive regulation of Toll signaling pathway

FB:FBrf0210737
PMID:20404143[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046872

metal ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000306

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Stewart BA (2002) Membrane trafficking in Drosophila wing and eye development. Semin Cell Dev Biol 13: 91-7 PubMed GONUTS page
  2. 2.0 2.1 González-Gaitán M (2003) Signal dispersal and transduction through the endocytic pathway. Nat Rev Mol Cell Biol 4: 213-24 PubMed GONUTS page
  3. Rives AF et al. (2006) Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing. Dev Biol 293: 268-83 PubMed GONUTS page
  4. 4.0 4.1 4.2 Lloyd TE et al. (2000) A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron 26: 45-50 PubMed GONUTS page
  5. Jékely G et al. (2005) Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration. Dev Cell 9: 197-207 PubMed GONUTS page
  6. Littleton JT (2000) A genomic analysis of membrane trafficking and neurotransmitter release in Drosophila. J Cell Biol 150: F77-82 PubMed GONUTS page
  7. 7.0 7.1 Huang HR et al. (2010) Endocytic pathway is required for Drosophila Toll innate immune signaling. Proc Natl Acad Sci U S A 107: 8322-7 PubMed GONUTS page
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