GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Hph
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Hph ( synonyms: 0303/04, 31543, CG1114, CG14665, CG31543, Dm.egl-9, Fatiga, HIF prolyl 4-hydroxylase, HIF-1a prolyl hyroxylase, PHD, anon-EST:Posey69, dHPH, dPHD2, dmHPH, fatiga, fga, hph, l(3)02255, l(3)S030304, lethal (3) S030304, prolyl-4-hydroxylase ) | |
| Protein Name(s) | HIF prolyl hydroxylase, | |
| External Links | ||
| FB | FBgn0086689 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001666 |
response to hypoxia |
FB:FBrf0141748 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001666 |
response to hypoxia |
FB:FBrf0152214 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005506 |
iron ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006974 |
response to DNA damage stimulus |
FB:FBrf0208272 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0145996 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008104 |
protein localization |
FB:FBrf0152214 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0016706 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0031418 |
L-ascorbic acid binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0031545 |
peptidyl-proline 4-dioxygenase activity |
FB:FBrf0141748 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0055114 |
oxidation-reduction process |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Bruick RK & McKnight SL (2001) A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294: 1337-40 PubMed GONUTS page
- ↑ 2.0 2.1 Lavista-Llanos S et al. (2002) Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar. Mol Cell Biol 22: 6842-53 PubMed GONUTS page
- ↑ Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
ilo |
o cont.pr |
r cont.z |
