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FB:Hmgcr
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Hmgcr ( synonyms: 3-Hydroxy-3-Methylglutaryl CoA Reductase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, BcDNA:LD15354, CG10367, Clb, DmHMG-CoAr, HMG-CoA reductase, HMGCR, HMGCR_Dm, HMGCo-A reductase, HMGCoA reductase, HMGCoAR, HMGCoARr, HMGCoAr, HmG-CoAR, Hmg, Hmg-CoA-reductase, bro1, bs32f05.y1, clb, columbus, hmgc, hmgcr, hmgrc, l(3)01152, l(3)04684, lethal (3) 04684 ) | |
| Protein Name(s) | HMG Coenzyme A reductase, | |
| External Links | ||
| FB | FBgn0263782 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004420 |
hydroxymethylglutaryl-CoA reductase (NADPH) activity |
FB:FBrf0101135 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004420 |
hydroxymethylglutaryl-CoA reductase (NADPH) activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:96159 |
F |
From FB |
||
| GO:0005622 |
intracellular |
FB:FBrf0160454 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005789 |
endoplasmic reticulum membrane |
FB:FBrf0123601 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005789 |
endoplasmic reticulum membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0007280 |
pole cell migration |
FB:FBrf0160886 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007280 |
pole cell migration |
FB:FBrf0190201 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004644 |
P |
From FB |
||
| GO:0007280 |
pole cell migration |
FB:FBrf0190201 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0029088 |
P |
From FB |
||
| GO:0007280 |
pole cell migration |
FB:FBrf0190201 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007626 |
locomotory behavior |
FB:FBrf0192310 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008299 |
isoprenoid biosynthetic process |
FB:FBrf0123601 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008299 |
isoprenoid biosynthetic process |
FB:FBrf0160454 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008299 |
isoprenoid biosynthetic process |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0008354 |
germ cell migration |
FB:FBrf0100771 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008354 |
germ cell migration |
FB:FBrf0107500 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008354 |
germ cell migration |
FB:FBrf0145696 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008354 |
germ cell migration |
FB:FBrf0151867 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008354 |
germ cell migration |
FB:FBrf0174539 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008406 |
gonad development |
FB:FBrf0102832 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0015936 |
coenzyme A metabolic process |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0018990 |
ecdysis, chitin-based cuticle |
FB:FBrf0209359 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035050 |
embryonic heart tube development |
FB:FBrf0194083 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035232 |
germ cell attraction |
FB:FBrf0102832 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035232 |
germ cell attraction |
FB:FBrf0160454 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035232 |
germ cell attraction |
FB:FBrf0160886 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035232 |
germ cell attraction |
FB:FBrf0179403 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0050661 |
NADP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0055114 |
oxidation-reduction process |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR002202 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Coffman CR (2003) Cell migration and programmed cell death of Drosophila germ cells. Ann N Y Acad Sci 995: 117-26 PubMed GONUTS page
- ↑ 2.0 2.1 Ribeiro C et al. (2003) Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila. Dev Biol 260: 1-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Deshpande G & Schedl P (2005) HMGCoA reductase potentiates hedgehog signaling in Drosophila melanogaster. Dev Cell 9: 629-38 PubMed GONUTS page
- ↑ Belgacem YH & Martin JR (2007) Hmgcr in the corpus allatum controls sexual dimorphism of locomotor activity and body size via the insulin pathway in Drosophila. PLoS One 2: e187 PubMed GONUTS page
- ↑ Moore LA et al. (1998) Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila. Development 125: 667-78 PubMed GONUTS page
- ↑ Wylie C (1999) Germ cells. Cell 96: 165-74 PubMed GONUTS page
- ↑ Müller HA (2002) Germ cell migration: as slow as molasses. Curr Biol 12: R612-4 PubMed GONUTS page
- ↑ Santos AC & Lehmann R (2004) Isoprenoids control germ cell migration downstream of HMGCoA reductase. Dev Cell 6: 283-93 PubMed GONUTS page
- ↑ 9.0 9.1 Howard K (1998) Organogenesis: Drosophila goes gonadal. Curr Biol 8: R415-7 PubMed GONUTS page
- ↑ Jones D et al. (2010) Suppressed production of methyl farnesoid hormones yields developmental defects and lethality in Drosophila larvae. Gen Comp Endocrinol 165: 244-54 PubMed GONUTS page
- ↑ Yi P et al. (2006) The mevalonate pathway controls heart formation in Drosophila by isoprenylation of Ggamma1. Science 313: 1301-3 PubMed GONUTS page
- ↑ Raz E (2004) Guidance of primordial germ cell migration. Curr Opin Cell Biol 16: 169-73 PubMed GONUTS page
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