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FB:HLH106

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) HLH106 ( synonyms: CG8522, Drosophila sterol regulatory element binding protein, HlH106, SREBP, Srebp, Sterol Regulatory Element Binding Protein, Sterol regulatory element-binding protein, dSREBP, dSrebp, dsrebp, l(3)76BDw, lethal (3) 76BDw, srebp, sterol regulatory element-binding protein, sterol-responsive element-binding protein )
Protein Name(s) Helix loop helix protein 106,
External Links
FB FBgn0261283

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000902

cell morphogenesis

FB:FBrf0212211
PMID:21041442[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

FB:FBrf0103020
PMID:9632664[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:4759168

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0116295

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0103020
PMID:9632664[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:4759168

C

From FB

GO:0005634

nucleus

FB:FBrf0116295

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0162253
PMID:12923525[3]

TAS: Traceable Author Statement

C

From FB

GO:0005789

endoplasmic reticulum membrane

FB:FBrf0103020
PMID:9632664[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0006633

fatty acid biosynthetic process

FB:FBrf0149184
PMID:11988558[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0006911

phagocytosis, engulfment

FB:FBrf0191376
PMID:16336044[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006994

positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway

FB:FBrf0103020
PMID:9632664[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0031965

nuclear membrane

FB:FBrf0103020
PMID:9632664[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0042304

regulation of fatty acid biosynthetic process

FB:FBrf0162253
PMID:12923525[3]

TAS: Traceable Author Statement

P

From FB

GO:0045893

positive regulation of transcription, DNA-dependent

FB:FBrf0162253
PMID:12923525[3]

TAS: Traceable Author Statement

P

From FB

GO:0055089

fatty acid homeostasis

FB:FBrf0194588
PMID:16753579[6]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. D'Ambrosio MV & Vale RD (2010) A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J Cell Biol 191: 471-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Rosenfeld JM & Osborne TF (1998) HLH106, a Drosophila sterol regulatory element-binding protein in a natural cholesterol auxotroph. J Biol Chem 273: 16112-21 PubMed GONUTS page
  3. 3.0 3.1 3.2 Rawson RB (2003) The SREBP pathway--insights from Insigs and insects. Nat Rev Mol Cell Biol 4: 631-40 PubMed GONUTS page
  4. Nohturfft A & Losick R (2002) Cell biology. Fats, flies, and palmitate. Science 296: 857-8 PubMed GONUTS page
  5. Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
  6. Kunte AS et al. (2006) Fatty acid auxotrophy in Drosophila larvae lacking SREBP. Cell Metab 3: 439-48 PubMed GONUTS page
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