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FB:HLH106
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | HLH106 ( synonyms: CG8522, Drosophila sterol regulatory element binding protein, HlH106, SREBP, Srebp, Sterol Regulatory Element Binding Protein, Sterol regulatory element-binding protein, dSREBP, dSrebp, dsrebp, l(3)76BDw, lethal (3) 76BDw, srebp, sterol regulatory element-binding protein, sterol-responsive element-binding protein ) | |
| Protein Name(s) | Helix loop helix protein 106, | |
| External Links | ||
| FB | FBgn0261283 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000902 |
cell morphogenesis |
FB:FBrf0212211 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
FB:FBrf0103020 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
NCBI_gi:4759168 |
F |
From FB |
||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0116295 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0103020 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
NCBI_gi:4759168 |
C |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0116295 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0162253 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005789 |
endoplasmic reticulum membrane |
FB:FBrf0103020 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006633 |
fatty acid biosynthetic process |
FB:FBrf0149184 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006994 |
positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway |
FB:FBrf0103020 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0031965 |
nuclear membrane |
FB:FBrf0103020 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0042304 |
regulation of fatty acid biosynthetic process |
FB:FBrf0162253 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
FB:FBrf0162253 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0055089 |
fatty acid homeostasis |
FB:FBrf0194588 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
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Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ D'Ambrosio MV & Vale RD (2010) A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J Cell Biol 191: 471-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Rosenfeld JM & Osborne TF (1998) HLH106, a Drosophila sterol regulatory element-binding protein in a natural cholesterol auxotroph. J Biol Chem 273: 16112-21 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Rawson RB (2003) The SREBP pathway--insights from Insigs and insects. Nat Rev Mol Cell Biol 4: 631-40 PubMed GONUTS page
- ↑ Nohturfft A & Losick R (2002) Cell biology. Fats, flies, and palmitate. Science 296: 857-8 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ Kunte AS et al. (2006) Fatty acid auxotrophy in Drosophila larvae lacking SREBP. Cell Metab 3: 439-48 PubMed GONUTS page