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FB:H
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | H ( synonyms: CG5460, Hairy, hairless ) | |
| Protein Name(s) | Hairless, | |
| External Links | ||
| FB | FBgn0001169 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003714 |
transcription corepressor activity |
FB:FBrf0076509 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0093584 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0141150 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0093584 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008052 |
sensory organ boundary specification |
FB:FBrf0128585 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008586 |
imaginal disc-derived wing vein morphogenesis |
FB:FBrf0191199 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008587 |
imaginal disc-derived wing margin morphogenesis |
FB:FBrf0191199 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010941 |
regulation of cell death |
FB:FBrf0207053 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016360 |
sensory organ precursor cell fate determination |
FB:FBrf0078010 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016360 |
sensory organ precursor cell fate determination |
FB:FBrf0078010 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016360 |
sensory organ precursor cell fate determination |
FB:FBrf0187452 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035019 |
somatic stem cell maintenance |
FB:FBrf0209974 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0078010 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004647 |
P |
From FB |
||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0078010 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0156161 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046331 |
lateral inhibition |
FB:FBrf0214518 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048190 |
wing disc dorsal/ventral pattern formation |
FB:FBrf0190133 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Brou C et al. (1994) Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-J kappa, by direct protein-protein interaction with Drosophila hairless. Genes Dev 8: 2491-503 PubMed GONUTS page
- ↑ 2.0 2.1 Majumdar A et al. (1997) strawberry notch encodes a conserved nuclear protein that functions downstream of Notch and regulates gene expression along the developing wing margin of Drosophila. Genes Dev 11: 1341-53 PubMed GONUTS page
- ↑ Nagel AC et al. (2000) Su(H)-independent activity of hairless during mechano-sensory organ formation in Drosophila. Mech Dev 94: 3-12 PubMed GONUTS page
- ↑ 4.0 4.1 Nagel AC et al. (2005) Hairless-mediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors. Mol Cell Biol 25: 10433-41 PubMed GONUTS page
- ↑ Protzer CE et al. (2008) Hairless induces cell death by downregulation of EGFR signalling activity. J Cell Sci 121: 3167-76 PubMed GONUTS page
- ↑ Castro B et al. (2005) Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless. Development 132: 3333-44 PubMed GONUTS page
- ↑ Bardin AJ et al. (2010) Transcriptional control of stem cell maintenance in the Drosophila intestine. Development 137: 705-14 PubMed GONUTS page
- ↑ Kadesch T (2000) Notch signaling: a dance of proteins changing partners. Exp Cell Res 260: 1-8 PubMed GONUTS page
- ↑ Koelzer S & Klein T (2006) Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless. Dev Biol 289: 77-90 PubMed GONUTS page
