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FB:Gug

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Gug ( synonyms: Atro, Atrophin, CG6964, GUG, atro, atrophin, grunge, gug, l(3)01323, l(3)03928, l(3)S146907, l(3)j5A3, l(3)rO116 )
Protein Name(s) Grunge,
External Links
FB FBgn0010825

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001654

eye development

FB:FBrf0190100
PMID:16445904[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003677

DNA binding

FB:FBrf0190568
PMID:16481466[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003714

transcription corepressor activity

FB:FBrf0144754
PMID:11792320[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0003714

transcription corepressor activity

FB:FBrf0144754
PMID:11792320[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0000606

F

From FB

GO:0003714

transcription corepressor activity

FB:FBrf0145548

NAS: Non-traceable Author Statement

F

From FB

GO:0004407

histone deacetylase activity

FB:FBrf0190568
PMID:16481466[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0005634

nucleus

FB:FBrf0144754
PMID:11792320[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005705

polytene chromosome interband

FB:FBrf0205145
PMID:18451879[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0007379

segment specification

FB:FBrf0179049
PMID:15166158[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007480

imaginal disc-derived leg morphogenesis

FB:FBrf0144818
PMID:11874908[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0190100
PMID:16445904[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0205145
PMID:18451879[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009880

embryonic pattern specification

FB:FBrf0144754
PMID:11792320[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035282

segmentation

FB:FBrf0144754
PMID:11792320[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

FB:FBrf0190100
PMID:16445904[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0003256

P

From FB

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

FB:FBrf0190100
PMID:16445904[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0004569

P

From FB

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

FB:FBrf0190100
PMID:16445904[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0004635

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0144754
PMID:11792320[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0070491

repressing transcription factor binding

FB:FBrf0144754
PMID:11792320[3]

IPI: Inferred from Physical Interaction

FB:FBgn0000606

F

From FB

GO:0070491

repressing transcription factor binding

FB:FBrf0144754
PMID:11792320[3]

IPI: Inferred from Physical Interaction

FB:FBgn0261434

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Charroux B et al. (2006) Atrophin contributes to the negative regulation of epidermal growth factor receptor signaling in Drosophila. Dev Biol 291: 278-90 PubMed GONUTS page
  2. 2.0 2.1 Wang L et al. (2006) Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors. Genes Dev 20: 525-30 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Zhang S et al. (2002) Drosophila atrophin homolog functions as a transcriptional corepressor in multiple developmental processes. Cell 108: 45-56 PubMed GONUTS page
  4. 4.0 4.1 Wang L et al. (2008) Atrophin recruits HDAC1/2 and G9a to modify histone H3K9 and to determine cell fates. EMBO Rep 9: 555-62 PubMed GONUTS page
  5. Luschnig S et al. (2004) An F1 genetic screen for maternal-effect mutations affecting embryonic pattern formation in Drosophila melanogaster. Genetics 167: 325-42 PubMed GONUTS page
  6. Erkner A et al. (2002) Grunge, related to human Atrophin-like proteins, has multiple functions in Drosophila development. Development 129: 1119-29 PubMed GONUTS page
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