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FB:Grip84

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Grip84 ( synonyms: CG3917, DGrip84, Dgrip84, Dgrips84, GCP2, grip84, l(1)((t))PG36, l(1)((t))PG66 )
Protein Name(s) gamma-tubulin ring protein 84,
External Links
FB FBgn0026430

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000922

spindle pole

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR007259

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0132100
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0007017

microtubule-based process

FB:FBrf0132100
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007020

microtubule nucleation

FB:FBrf0107918
PMID:10037793[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0007020

microtubule nucleation

FB:FBrf0132373
PMID:11134079[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0007052

mitotic spindle organization

FB:FBrf0200397
PMID:17412918[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007067

mitosis

FB:FBrf0191157
PMID:16236791[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007067

mitosis

FB:FBrf0207149
PMID:18463163[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007126

meiosis

FB:FBrf0191157
PMID:16236791[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007283

spermatogenesis

FB:FBrf0191157
PMID:16236791[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008017

microtubule binding

FB:FBrf0132100
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0008275

gamma-tubulin small complex

FB:FBrf0107918
PMID:10037793[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0008275

gamma-tubulin small complex

FB:FBrf0122447

NAS: Non-traceable Author Statement

C

From FB

GO:0008275

gamma-tubulin small complex

FB:FBrf0132373
PMID:11134079[3]

IPI: Inferred from Physical Interaction

FB:FBgn0001612

C

From FB

GO:0008275

gamma-tubulin small complex

FB:FBrf0132373
PMID:11134079[3]

IPI: Inferred from Physical Interaction

FB:FBgn0260639

C

From FB

GO:0015631

tubulin binding

FB:FBrf0105495

NAS: Non-traceable Author Statement

F

From FB

GO:0030953

astral microtubule organization

FB:FBrf0191157
PMID:16236791[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043015

gamma-tubulin binding

FB:FBrf0159185
PMID:12631720[7]

IDA: Inferred from Direct Assay

F

From FB

GO:0051225

spindle assembly

FB:FBrf0191157
PMID:16236791[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051297

centrosome organization

FB:FBrf0191157
PMID:16236791[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051297

centrosome organization

FB:FBrf0200397
PMID:17412918[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051297

centrosome organization

FB:FBrf0212030
PMID:20818332[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051726

regulation of cell cycle

FB:FBrf0194177
PMID:17068266[9]

IMP: Inferred from Mutant Phenotype

P

From FB

colocalizes_with

GO:0005813

centrosome

FB:FBrf0107918
PMID:10037793[2]

IDA: Inferred from Direct Assay

C

From FB

colocalizes_with

GO:0072686

mitotic spindle

FB:FBrf0107918
PMID:10037793[2]

IDA: Inferred from Direct Assay

C

From FB

contributes_to

GO:0051011

microtubule minus-end binding

FB:FBrf0132373
PMID:11134079[3]

IDA: Inferred from Direct Assay

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Oegema K et al. (1999) Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules. J Cell Biol 144: 721-33 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gunawardane RN et al. (2000) Characterization and reconstitution of Drosophila gamma-tubulin ring complex subunits. J Cell Biol 151: 1513-24 PubMed GONUTS page
  4. 4.0 4.1 Goshima G et al. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-21 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Colombié N et al. (2006) The Drosophila gamma-tubulin small complex subunit Dgrip84 is required for structural and functional integrity of the spindle apparatus. Mol Biol Cell 17: 272-82 PubMed GONUTS page
  6. Ducat D et al. (2008) Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Mol Biol Cell 19: 3097-110 PubMed GONUTS page
  7. Gunawardane RN et al. (2003) Characterization of a new gammaTuRC subunit with WD repeats. Mol Biol Cell 14: 1017-26 PubMed GONUTS page
  8. Müller H et al. (2010) Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J 29: 3344-57 PubMed GONUTS page
  9. Müller H et al. (2006) A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint. Science 314: 654-7 PubMed GONUTS page
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