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FB:Gen
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Gen ( synonyms: BcDNA:GM10765, CG10670, DmGEN, mus324, mutagen-sensitive 324 ) | |
| Protein Name(s) | XPG-like endonuclease, | |
| External Links | ||
| FB | FBgn0263831 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000014 |
single-stranded DNA specific endodeoxyribonuclease activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0000737 |
DNA catabolic process, endonucleolytic |
FB:FBrf0180600 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0000738 |
DNA catabolic process, exonucleolytic |
FB:FBrf0180600 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0003684 |
damaged DNA binding |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004519 |
endonuclease activity |
FB:FBrf0130073 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004520 |
endodeoxyribonuclease activity |
FB:FBrf0180600 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001596 |
C |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0202082 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006284 |
base-excision repair |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006302 |
double-strand break repair |
FB:FBrf0201349 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008310 |
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity |
FB:FBrf0180600 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0008311 |
double-stranded DNA specific 3'-5' exodeoxyribonuclease activity |
FB:FBrf0180600 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0035312 |
5'-3' exodeoxyribonuclease activity |
FB:FBrf0180600 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0048256 |
flap endonuclease activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0001596 |
F |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Ishikawa G et al. (2004) DmGEN, a novel RAD2 family endo-exonuclease from Drosophila melanogaster. Nucleic Acids Res 32: 6251-9 PubMed GONUTS page
- ↑ Sekelsky JJ et al. (2000) DNA repair in Drosophila: insights from the Drosophila genome sequence. J Cell Biol 150: F31-6 PubMed GONUTS page
- ↑ Kanai Y et al. (2007) DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork. FEBS J 274: 3914-27 PubMed GONUTS page
- ↑ Wei DS & Rong YS (2007) A genetic screen for DNA double-strand break repair mutations in Drosophila. Genetics 177: 63-77 PubMed GONUTS page
