GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Gef26
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Gef26 ( synonyms: CG9491, Dizzy, GEF, PDF-GEF Dizzy, PDZ-GEF, PDZ-GEF/Dizzy, dPDZ-GEF, dizzy, dzy, l(2)k13720 ) | |
| Protein Name(s) | Gef26, | |
| External Links | ||
| FB | FBgn0021873 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000165 |
MAPK cascade |
FB:FBrf0152217 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003079 |
P |
From FB |
||
| GO:0000165 |
MAPK cascade |
FB:FBrf0152217 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003256 |
P |
From FB |
||
| GO:0000165 |
MAPK cascade |
FB:FBrf0152217 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010269 |
P |
From FB |
||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
FB:FBrf0126026 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
FB:FBrf0141911 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005622 |
intracellular |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0006930 |
substrate-dependent cell migration, cell extension |
FB:FBrf0192108 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007412 |
axon target recognition |
FB:FBrf0146405 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0192108 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007485 |
imaginal disc-derived male genitalia development |
FB:FBrf0192108 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016476 |
regulation of embryonic cell shape |
FB:FBrf0192108 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0017132 |
cyclic nucleotide-dependent guanyl-nucleotide exchange factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:AF115480 |
F |
From FB |
||
| GO:0030718 |
germ-line stem cell maintenance |
FB:FBrf0190226 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035099 |
hemocyte migration |
FB:FBrf0192108 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045314 |
regulation of compound eye photoreceptor development |
FB:FBrf0152217 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0152217 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0190226 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0192108 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051056 |
regulation of small GTPase mediated signal transduction |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Lee JH et al. (2002) Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway. Mol Cell Biol 22: 7658-66 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Huelsmann S et al. (2006) The PDZ-GEF dizzy regulates cell shape of migrating macrophages via Rap1 and integrins in the Drosophila embryo. Development 133: 2915-24 PubMed GONUTS page
- ↑ 3.0 3.1 Wang H et al. (2006) Rap-GEF signaling controls stem cell anchoring to their niche through regulating DE-cadherin-mediated cell adhesion in the Drosophila testis. Dev Cell 10: 117-26 PubMed GONUTS page
