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FB:Gcn2

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Gcn2 ( synonyms: CG1609, DGCN2, EIF2, GCN2, dGCN2, general control nonderepressing 2 kinase )
Protein Name(s) Gcn2,
External Links
FB FBgn0019990

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000398

nuclear mRNA splicing, via spliceosome

FB:FBrf0207172
PMID:18981222[1]

IC: Inferred by Curator

GO:0071011
GO:0071013

P

From FB

GO:0004672

protein kinase activity

FB:FBrf0132098
PMID:10908587[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0004686

elongation factor-2 kinase activity

FB:FBrf0093692
PMID:9139706[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0004686

elongation factor-2 kinase activity

FB:FBrf0102992
PMID:9649537[4]

IDA: Inferred from Direct Assay

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

From FB

GO:0005829

cytosol

FB:FBrf0093692
PMID:9139706[3]

IC: Inferred by Curator

GO:0004686

C

From FB

GO:0006417

regulation of translation

FB:FBrf0093692
PMID:9139706[3]

IC: Inferred by Curator

GO:0004686

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0093692
PMID:9139706[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0045793

positive regulation of cell size

FB:FBrf0209636
PMID:19917724[5]

IGI: Inferred from Genetic Interaction

FB:FBgn0005198

P

From FB

GO:0071011

precatalytic spliceosome

FB:FBrf0207172
PMID:18981222[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0071013

catalytic step 2 spliceosome

FB:FBrf0207172
PMID:18981222[1]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Herold N et al. (2009) Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Mol Cell Biol 29: 281-301 PubMed GONUTS page
  2. 2.0 2.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Santoyo J et al. (1997) Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2alpha (eIF-2alpha) kinase from Drosophila melanogaster. Homology To yeast GCN2 protein kinase. J Biol Chem 272: 12544-50 PubMed GONUTS page
  4. Olsen DS et al. (1998) Isolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinase. Genetics 149: 1495-509 PubMed GONUTS page
  5. Cully M et al. (2010) A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1. Mol Cell Biol 30: 481-95 PubMed GONUTS page
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