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FB:Gap1

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Gap1 ( synonyms: CG6721, GAP, GAP1, GTPase activating protein 1, GTPase activating protein1, Gap, Gap 1, Ras-GAP, gap, gap1, mip, more inner photoreceptors, rI533, rasGAP, seven extra, sextra, sxt )
Protein Name(s) GTPase-activating protein 1,
External Links
FB FBgn0004390

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005099

Ras GTPase activator activity

FB:FBrf0055542
PMID:1547500[1]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0005099

Ras GTPase activator activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:U20238

F

From FB

GO:0005099

Ras GTPase activator activity

FB:FBrf0124062

NAS: Non-traceable Author Statement

F

From FB

GO:0005543

phospholipid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From FB

GO:0005622

intracellular

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001936
InterPro:IPR008936

C

From FB

GO:0005886

plasma membrane

FB:FBrf0107943
PMID:10330487[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0007062

sister chromatid cohesion

FB:FBrf0135802
PMID:11290718[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007067

mitosis

FB:FBrf0135802
PMID:11290718[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007265

Ras protein signal transduction

FB:FBrf0055542
PMID:1547500[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007265

Ras protein signal transduction

FB:FBrf0124062

NAS: Non-traceable Author Statement

P

From FB

GO:0007426

tracheal outgrowth, open tracheal system

FB:FBrf0190195
PMID:16326394[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0193945
PMID:16648592[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008293

torso signaling pathway

FB:FBrf0111327
PMID:10494038[6]

NAS: Non-traceable Author Statement

P

From FB

GO:0008595

anterior/posterior axis specification, embryo

FB:FBrf0111327
PMID:10494038[6]

TAS: Traceable Author Statement

P

From FB

GO:0016321

female meiosis chromosome segregation

FB:FBrf0135802
PMID:11290718[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045678

positive regulation of R7 cell differentiation

FB:FBrf0190087
PMID:16600208[7]

IGI: Inferred from Genetic Interaction

FB:FBgn0086361

P

From FB

GO:0046580

negative regulation of Ras protein signal transduction

FB:FBrf0079934
PMID:7888014[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0051056

regulation of small GTPase mediated signal transduction

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001936

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Gaul U et al. (1992) A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase. Cell 68: 1007-19 PubMed GONUTS page
  2. Powe AC Jr et al. (1999) In vivo functional analysis of Drosophila Gap1: involvement of Ca2+ and IP4 regulation. Mech Dev 81: 89-101 PubMed GONUTS page
  3. 3.0 3.1 3.2 Dobie KW et al. (2001) Identification of chromosome inheritance modifiers in Drosophila melanogaster. Genetics 157: 1623-37 PubMed GONUTS page
  4. Cabernard C & Affolter M (2005) Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila. Dev Cell 9: 831-42 PubMed GONUTS page
  5. Dworkin I & Gibson G (2006) Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. Genetics 173: 1417-31 PubMed GONUTS page
  6. 6.0 6.1 Baek KH & Lee KY (1999) Signal transduction pathway for anterior-posterior development in Drosophila. J Biomed Sci 6: 314-9 PubMed GONUTS page
  7. Baril C & Therrien M (2006) Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila. Dev Biol 294: 232-45 PubMed GONUTS page
  8. Chang HC et al. (1995) phyllopod functions in the fate determination of a subset of photoreceptors in Drosophila. Cell 80: 463-72 PubMed GONUTS page
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