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FB:Ext2
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Ext2 ( synonyms: BcDNA:GH02288, CG33038, CG8433, DEXT2, DExt2, Sotv, sister of tout-velu, sister-of-tout-velu, sotv ) | |
| Protein Name(s) | Ext2, | |
| External Links | ||
| FB | FBgn0029175 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
FB:FBrf0174560 |
IPI: Inferred from Physical Interaction |
FB:FBgn0020245 |
F |
From FB |
||
| GO:0005783 |
endoplasmic reticulum |
FB:FBrf0174560 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005794 |
Golgi apparatus |
FB:FBrf0174560 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006024 |
glycosaminoglycan biosynthetic process |
FB:FBrf0174560 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006044 |
N-acetylglucosamine metabolic process |
FB:FBrf0184304 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0174560 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0174569 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008101 |
decapentaplegic signaling pathway |
FB:FBrf0174560 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008101 |
decapentaplegic signaling pathway |
FB:FBrf0174569 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008375 |
acetylglucosaminyltransferase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:AF089748 |
F |
From FB |
||
| GO:0008375 |
acetylglucosaminyltransferase activity |
FB:FBrf0155642 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0015012 |
heparan sulfate proteoglycan biosynthetic process |
FB:FBrf0155642 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0015012 |
heparan sulfate proteoglycan biosynthetic process |
FB:FBrf0190890 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0015014 |
heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process |
FB:FBrf0167537 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0015020 |
glucuronosyltransferase activity |
FB:FBrf0155642 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0174560 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0174569 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030206 |
chondroitin sulfate biosynthetic process |
FB:FBrf0174569 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030210 |
heparin biosynthetic process |
FB:FBrf0174569 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031227 |
intrinsic to endoplasmic reticulum membrane |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0050508 |
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity |
FB:FBrf0184304 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0050509 |
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
FB:FBrf0184304 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Han C et al. (2004) Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation. Development 131: 1563-75 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Bornemann DJ et al. (2004) Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways. Development 131: 1927-38 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Wilson IB (2002) Glycosylation of proteins in plants and invertebrates. Curr Opin Struct Biol 12: 569-77 PubMed GONUTS page
- ↑ Izumikawa T et al. (2006) Heparan sulfate polymerization in Drosophila. J Biol Chem 281: 1929-34 PubMed GONUTS page
- ↑ Takei Y et al. (2004) Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans. Development 131: 73-82 PubMed GONUTS page
