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FB:Egfr

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Egfr ( synonyms: C-erb, CG10079, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER-Ellipse, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, Degfr, Der, DmHD-33, Drosophila epidermal growth factor receptor homologue, EFG-R, EGF Receptor, EGF receptor, EGF-R, EGF-receptor, EGFR, EGFr, EGfr, EK2-6, Egf, Egf receptor, Egf-r, EgfR, El, Ellipse, Ellipse torpedo, Elp, Elp-1, Elp-B1, Elp-B1RB1, Epidermal Growth Factor Receptor, Epidermal growth factor Receptor, HD-33, TOP, Torpedo, Torpedo/DER, Torpedo/Egfr, c-erbB, d-egf-r, dEGFR, dEGFR1, dEgfr, der, egfr, epidermal growth factor receptor, faint little ball, flb, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57EFa, l(2)57Ea, mor1, morphological defects 1, top, top/DER, top/flb, torpedo, torpedo/DER, torpedo/Egfr, torpedo/egfr )
Protein Name(s) Epidermal growth factor receptor,
External Links
FB FBgn0003731

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000086

G2/M transition of mitotic cell cycle

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0000578

embryonic axis specification

FB:FBrf0136839

NAS: Non-traceable Author Statement

P

From FB

GO:0001654

eye development

FB:FBrf0167472
PMID:14536058[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001709

cell fate determination

FB:FBrf0102528
PMID:9631645[3]

TAS: Traceable Author Statement

P

From FB

GO:0001709

cell fate determination

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0001709

cell fate determination

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0001742

oenocyte differentiation

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0001745

compound eye morphogenesis

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0001751

compound eye photoreceptor cell differentiation

FB:FBrf0141762
PMID:11735386[5]

TAS: Traceable Author Statement

P

From FB

GO:0001751

compound eye photoreceptor cell differentiation

FB:FBrf0189914
PMID:16377567[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001752

compound eye photoreceptor fate commitment

FB:FBrf0102528
PMID:9631645[3]

TAS: Traceable Author Statement

P

From FB

GO:0002009

morphogenesis of an epithelium

FB:FBrf0106865
PMID:9927461[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003015

heart process

FB:FBrf0210954
PMID:20523889[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0118626

NAS: Non-traceable Author Statement

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0123367

NAS: Non-traceable Author Statement

F

From FB

GO:0004713

protein tyrosine kinase activity

FB:FBrf0132098
PMID:10908587[9]

NAS: Non-traceable Author Statement

F

From FB

GO:0004888

transmembrane signaling receptor activity

FB:FBrf0160750
PMID:12879448[10]

TAS: Traceable Author Statement

F

From FB

GO:0005006

epidermal growth factor-activated receptor activity

FB:FBrf0042044
PMID:2982499[11]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005006

epidermal growth factor-activated receptor activity

FB:FBrf0102528
PMID:9631645[3]

TAS: Traceable Author Statement

F

From FB

GO:0005006

epidermal growth factor-activated receptor activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P00533

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR006211
InterPro:IPR017441

F

From FB

GO:0005886

plasma membrane

FB:FBrf0093706
PMID:9154002[12]

TAS: Traceable Author Statement

C

From FB

GO:0005887

integral to plasma membrane

FB:FBrf0123367

NAS: Non-traceable Author Statement

C

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR006211
InterPro:IPR008266
InterPro:IPR020635

P

From FB

GO:0006916

anti-apoptosis

FB:FBrf0144793
PMID:11832236[13]

NAS: Non-traceable Author Statement

P

From FB

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006211

P

From FB

GO:0007173

epidermal growth factor receptor signaling pathway

FB:FBrf0093706
PMID:9154002[12]

TAS: Traceable Author Statement

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0132450
PMID:11141565[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0160886
PMID:12885551[15]

TAS: Traceable Author Statement

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0187407
PMID:16054027[16]

IGI: Inferred from Genetic Interaction

FB:FBgn0020224

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0187407
PMID:16054027[16]

IGI: Inferred from Genetic Interaction

FB:FBgn0032006

P

From FB

GO:0007298

border follicle cell migration

FB:FBrf0193922
PMID:16712835[17]

IGI: Inferred from Genetic Interaction

FB:FBgn0032006

P

From FB

GO:0007309

oocyte axis specification

FB:FBrf0193906
PMID:16908845[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007310

oocyte dorsal/ventral axis specification

FB:FBrf0103246
PMID:9642168[19]

NAS: Non-traceable Author Statement

P

From FB

GO:0007310

oocyte dorsal/ventral axis specification

FB:FBrf0123367

NAS: Non-traceable Author Statement

P

From FB

GO:0007314

oocyte anterior/posterior axis specification

FB:FBrf0103246
PMID:9642168[19]

NAS: Non-traceable Author Statement

P

From FB

GO:0007314

oocyte anterior/posterior axis specification

FB:FBrf0123367

NAS: Non-traceable Author Statement

P

From FB

GO:0007314

oocyte anterior/posterior axis specification

FB:FBrf0128774
PMID:10878576[20]

NAS: Non-traceable Author Statement

P

From FB

GO:0007346

regulation of mitotic cell cycle

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0007350

blastoderm segmentation

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007367

segment polarity determination

FB:FBrf0187474
PMID:15930099[21]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007369

gastrulation

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007390

germ-band shortening

FB:FBrf0090577
PMID:8946251[22]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007390

germ-band shortening

FB:FBrf0106865
PMID:9927461[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007390

germ-band shortening

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0106865
PMID:9927461[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007420

brain development

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007421

stomatogastric nervous system development

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0162204
PMID:12967983[23]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0125237
PMID:10684581[24]

TAS: Traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0131240
PMID:11063940[25]

TAS: Traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0161023
PMID:12791296[26]

TAS: Traceable Author Statement

P

From FB

GO:0007431

salivary gland development

FB:FBrf0106865
PMID:9927461[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007443

Malpighian tubule morphogenesis

FB:FBrf0106865
PMID:9927461[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007443

Malpighian tubule morphogenesis

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007444

imaginal disc development

FB:FBrf0129912
PMID:10934021[27]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007444

imaginal disc development

FB:FBrf0136839

NAS: Non-traceable Author Statement

P

From FB

GO:0007444

imaginal disc development

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007447

imaginal disc pattern formation

FB:FBrf0136839

NAS: Non-traceable Author Statement

P

From FB

GO:0007455

eye-antennal disc morphogenesis

FB:FBrf0192868
PMID:16963016[28]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007458

progression of morphogenetic furrow involved in compound eye morphogenesis

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0007469

antennal development

FB:FBrf0145168
PMID:11875444[29]

NAS: Non-traceable Author Statement

P

From FB

GO:0007472

wing disc morphogenesis

FB:FBrf0162081
PMID:12930782[30]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007473

wing disc proximal/distal pattern formation

FB:FBrf0158727
PMID:12717815[31]

TAS: Traceable Author Statement

P

From FB

GO:0007474

imaginal disc-derived wing vein specification

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0130152
PMID:10995384[32]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0145168
PMID:11875444[29]

NAS: Non-traceable Author Statement

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0162081
PMID:12930782[30]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0167472
PMID:14536058[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0193945
PMID:16648592[33]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007477

notum development

FB:FBrf0130152
PMID:10995384[32]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007479

leg disc proximal/distal pattern formation

FB:FBrf0151696
PMID:12181568[34]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007479

leg disc proximal/distal pattern formation

FB:FBrf0151711
PMID:12181552[35]

TAS: Traceable Author Statement

P

From FB

GO:0007479

leg disc proximal/distal pattern formation

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0007482

haltere development

FB:FBrf0195051
PMID:16815386[36]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008071

maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded

FB:FBrf0045776
PMID:3107840[37]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008284

positive regulation of cell proliferation

FB:FBrf0206542
PMID:19141677[38]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008284

positive regulation of cell proliferation

FB:FBrf0212840
PMID:21176204[39]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008313

gurken-activated receptor activity

FB:FBrf0123367

NAS: Non-traceable Author Statement

F

From FB

GO:0008314

gurken receptor signaling pathway

FB:FBrf0123367

NAS: Non-traceable Author Statement

P

From FB

GO:0008406

gonad development

FB:FBrf0213539
PMID:21377458[40]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0102528
PMID:9631645[3]

TAS: Traceable Author Statement

P

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0183863
PMID:15766758[41]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009880

embryonic pattern specification

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0009880

embryonic pattern specification

FB:FBrf0200831
PMID:17898168[42]

IGI: Inferred from Genetic Interaction

FB:FBgn0262656

P

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0123367

NAS: Non-traceable Author Statement

P

From FB

GO:0009952

anterior/posterior pattern specification

FB:FBrf0107500
PMID:9988212[43]

TAS: Traceable Author Statement

P

From FB

GO:0009953

dorsal/ventral pattern formation

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0016020

membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000494
InterPro:IPR006211

C

From FB

GO:0016203

muscle attachment

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0016318

ommatidial rotation

FB:FBrf0167498
PMID:14507785[44]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016318

ommatidial rotation

FB:FBrf0167499
PMID:14507782[45]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016330

second mitotic wave involved in compound eye morphogenesis

FB:FBrf0134491
PMID:11257224[46]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016330

second mitotic wave involved in compound eye morphogenesis

FB:FBrf0141762
PMID:11735386[5]

TAS: Traceable Author Statement

P

From FB

GO:0016330

second mitotic wave involved in compound eye morphogenesis

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0016333

morphogenesis of follicular epithelium

FB:FBrf0101997
PMID:9504923[47]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016337

cell-cell adhesion

FB:FBrf0192922
PMID:16831830[48]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0019904

protein domain specific binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000308

F

From FB

GO:0022008

neurogenesis

FB:FBrf0200831
PMID:17898168[42]

IGI: Inferred from Genetic Interaction

FB:FBgn0262656

P

From FB

GO:0030031

cell projection assembly

FB:FBrf0152247
PMID:12198500[49]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030381

chorion-containing eggshell pattern formation

FB:FBrf0139680
PMID:11606538[50]

IGI: Inferred from Genetic Interaction

FB:FBgn0003205

P

From FB

GO:0030381

chorion-containing eggshell pattern formation

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0030718

germ-line stem cell maintenance

FB:FBrf0190226
PMID:16399083[51]

IGI: Inferred from Genetic Interaction

FB:FBgn0021873

P

From FB

GO:0035088

establishment or maintenance of apical/basal cell polarity

FB:FBrf0193906
PMID:16908845[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035160

maintenance of epithelial integrity, open tracheal system

FB:FBrf0192922
PMID:16831830[48]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035202

tracheal pit formation in open tracheal system

FB:FBrf0161023
PMID:12791296[26]

TAS: Traceable Author Statement

P

From FB

GO:0035225

determination of genital disc primordium

FB:FBrf0187379
PMID:15893978[52]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035277

spiracle morphogenesis, open tracheal system

FB:FBrf0187474
PMID:15930099[21]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035309

wing and notum subfield formation

FB:FBrf0128387
PMID:10860999[53]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035310

notum cell fate specification

FB:FBrf0130152
PMID:10995384[32]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042676

compound eye cone cell fate commitment

FB:FBrf0151870
PMID:12419199[54]

TAS: Traceable Author Statement

P

From FB

GO:0042676

compound eye cone cell fate commitment

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0042694

muscle cell fate specification

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0043066

negative regulation of apoptotic process

FB:FBrf0193620
PMID:17055987[55]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045165

cell fate commitment

FB:FBrf0136839

NAS: Non-traceable Author Statement

P

From FB

GO:0045466

R7 cell differentiation

FB:FBrf0161963
PMID:14505358[56]

TAS: Traceable Author Statement

P

From FB

GO:0045468

regulation of R8 cell spacing in compound eye

FB:FBrf0144824
PMID:11880339[57]

NAS: Non-traceable Author Statement

P

From FB

GO:0045468

regulation of R8 cell spacing in compound eye

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0045610

regulation of hemocyte differentiation

FB:FBrf0180639
PMID:15381778[58]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045749

negative regulation of S phase of mitotic cell cycle

FB:FBrf0187405
PMID:15809036[59]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046673

negative regulation of compound eye retinal cell programmed cell death

FB:FBrf0156100
PMID:12547518[60]

TAS: Traceable Author Statement

P

From FB

GO:0046673

negative regulation of compound eye retinal cell programmed cell death

FB:FBrf0180487
PMID:15511643[61]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046843

dorsal appendage formation

FB:FBrf0193282
PMID:17008069[62]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046845

branched duct epithelial cell fate determination, open tracheal system

FB:FBrf0125237
PMID:10684581[24]

TAS: Traceable Author Statement

P

From FB

GO:0046845

branched duct epithelial cell fate determination, open tracheal system

FB:FBrf0131240
PMID:11063940[25]

TAS: Traceable Author Statement

P

From FB

GO:0048139

female germ-line cyst encapsulation

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0048140

male germ-line cyst encapsulation

FB:FBrf0158927
PMID:12648473[4]

TAS: Traceable Author Statement

P

From FB

GO:0048149

behavioral response to ethanol

FB:FBrf0208186
PMID:19464045[63]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048477

oogenesis

FB:FBrf0136839

NAS: Non-traceable Author Statement

P

From FB

GO:0048546

digestive tract morphogenesis

FB:FBrf0212840
PMID:21176204[39]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0056571
PMID:1634999[64]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0135707
PMID:11301250[65]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048865

stem cell fate commitment

FB:FBrf0210887
PMID:20463031[66]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0061331

epithelial cell proliferation involved in Malpighian tubule morphogenesis

FB:FBrf0102951
PMID:9637680[67]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0061331

epithelial cell proliferation involved in Malpighian tubule morphogenesis

FB:FBrf0144843
PMID:11861476[68]

IMP: Inferred from Mutant Phenotype

P

From FB


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Notes

References

See Help:References for how to manage references in GONUTS.
  1. ↑ 1.0 1.1 1.2 1.3 1.4 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
  2. ↑ 2.0 2.1 Weber U et al. (2003) Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development. Dev Cell 5: 559-70 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 Bier E (1998) Localized activation of RTK/MAPK pathways during Drosophila development. Bioessays 20: 189-94 PubMed GONUTS page
  4. ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 4.18 4.19 4.20 4.21 4.22 Shilo BZ (2003) Signaling by the Drosophila epidermal growth factor receptor pathway during development. Exp Cell Res 284: 140-9 PubMed GONUTS page
  5. ↑ 5.0 5.1 Baker NE (2001) Cell proliferation, survival, and death in the Drosophila eye. Semin Cell Dev Biol 12: 499-507 PubMed GONUTS page
  6. ↑ Li X & Carthew RW (2005) A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell 123: 1267-77 PubMed GONUTS page
  7. ↑ 7.0 7.1 7.2 7.3 7.4 Liu X et al. (1999) Identification of genes controlling malpighian tubule and other epithelial morphogenesis in Drosophila melanogaster. Genetics 151: 685-95 PubMed GONUTS page
  8. ↑ Yu L et al. (2010) Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila. PLoS Genet 6: e1000969 PubMed GONUTS page
  9. ↑ 9.0 9.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  10. ↑ López-Schier H (2003) The polarisation of the anteroposterior axis in Drosophila. Bioessays 25: 781-91 PubMed GONUTS page
  11. ↑ Livneh E et al. (1985) The Drosophila EGF receptor gene homolog: conservation of both hormone binding and kinase domains. Cell 40: 599-607 PubMed GONUTS page
  12. ↑ 12.0 12.1 Schweitzer R & Shilo BZ (1997) A thousand and one roles for the Drosophila EGF receptor. Trends Genet 13: 191-6 PubMed GONUTS page
  13. ↑ White K (2002) Signaling survival: how axons rescue their glia. Dev Cell 2: 128-30 PubMed GONUTS page
  14. ↑ Duchek P & Rørth P (2001) Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis. Science 291: 131-3 PubMed GONUTS page
  15. ↑ Ribeiro C et al. (2003) Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila. Dev Biol 260: 1-8 PubMed GONUTS page
  16. ↑ 16.0 16.1 Jékely G et al. (2005) Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration. Dev Cell 9: 197-207 PubMed GONUTS page
  17. ↑ McDonald JA et al. (2006) Multiple EGFR ligands participate in guiding migrating border cells. Dev Biol 296: 94-103 PubMed GONUTS page
  18. ↑ 18.0 18.1 Poulton JS & Deng WM (2006) Dystroglycan down-regulation links EGF receptor signaling and anterior-posterior polarity formation in the Drosophila oocyte. Proc Natl Acad Sci U S A 103: 12775-80 PubMed GONUTS page
  19. ↑ 19.0 19.1 Cooperstock RL & Lipshitz HD (1997) Control of mRNA stability and translation during Drosophila development. Semin Cell Dev Biol 8: 541-9 PubMed GONUTS page
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  21. ↑ 21.0 21.1 Merabet S et al. (2005) Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis. Development 132: 3093-102 PubMed GONUTS page
  22. ↑ Goldman-Levi R et al. (1996) Cellular pathways acting along the germband and in the amnioserosa may participate in germband retraction of the Drosophila melanogaster embryo. Int J Dev Biol 40: 1043-51 PubMed GONUTS page
  23. ↑ Sepp KJ & Auld VJ (2003) Reciprocal interactions between neurons and glia are required for Drosophila peripheral nervous system development. J Neurosci 23: 8221-30 PubMed GONUTS page
  24. ↑ 24.0 24.1 Zelzer E & Shilo BZ (2000) Cell fate choices in Drosophila tracheal morphogenesis. Bioessays 22: 219-26 PubMed GONUTS page
  25. ↑ 25.0 25.1 Affolter M & Shilo BZ (2000) Genetic control of branching morphogenesis during Drosophila tracheal development. Curr Opin Cell Biol 12: 731-5 PubMed GONUTS page
  26. ↑ 26.0 26.1 Uv A et al. (2003) Drosophila tracheal morphogenesis: intricate cellular solutions to basic plumbing problems. Trends Cell Biol 13: 301-9 PubMed GONUTS page
  27. ↑ Kubota K et al. (2000) EGF receptor attenuates Dpp signaling and helps to distinguish the wing and leg cell fates in Drosophila. Development 127: 3769-76 PubMed GONUTS page
  28. ↑ Brown KE et al. (2006) Epithelial cell adhesion in the developing Drosophila retina is regulated by Atonal and the EGF receptor pathway. Dev Biol 300: 710-21 PubMed GONUTS page
  29. ↑ 29.0 29.1 Curtiss J et al. (2002) Selector and signalling molecules cooperate in organ patterning. Nat Cell Biol 4: E48-51 PubMed GONUTS page
  30. ↑ 30.0 30.1 Pallavi SK & Shashidhara LS (2003) Egfr/Ras pathway mediates interactions between peripodial and disc proper cells in Drosophila wing discs. Development 130: 4931-41 PubMed GONUTS page
  31. ↑ De Celis JF (2003) Pattern formation in the Drosophila wing: The development of the veins. Bioessays 25: 443-51 PubMed GONUTS page
  32. ↑ 32.0 32.1 32.2 Wang SH et al. (2000) Dual role for Drosophila epidermal growth factor receptor signaling in early wing disc development. Genes Dev 14: 2271-6 PubMed GONUTS page
  33. ↑ Dworkin I & Gibson G (2006) Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. Genetics 173: 1417-31 PubMed GONUTS page
  34. ↑ Campbell G (2002) Distalization of the Drosophila leg by graded EGF-receptor activity. Nature 418: 781-5 PubMed GONUTS page
  35. ↑ Mann RS & Casares F (2002) Developmental biology: signalling legacies. Nature 418: 737-9 PubMed GONUTS page
  36. ↑ Pallavi SK et al. (2006) Negative regulation of Egfr/Ras pathway by Ultrabithorax during haltere development in Drosophila. Dev Biol 296: 340-52 PubMed GONUTS page
  37. ↑ Schüpbach T (1987) Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster. Cell 49: 699-707 PubMed GONUTS page
  38. ↑ Jiang H & Edgar BA (2009) EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development 136: 483-93 PubMed GONUTS page
  39. ↑ 39.0 39.1 Buchon N et al. (2010) Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol 8: 152 PubMed GONUTS page
  40. ↑ Weyers JJ et al. (2011) A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway. Dev Biol 353: 217-28 PubMed GONUTS page
  41. ↑ Ralston A & Blair SS (2005) Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone. Dev Biol 280: 187-200 PubMed GONUTS page
  42. ↑ 42.0 42.1 Orian A et al. (2007) A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development. Proc Natl Acad Sci U S A 104: 15771-6 PubMed GONUTS page
  43. ↑ Wylie C (1999) Germ cells. Cell 96: 165-74 PubMed GONUTS page
  44. ↑ Brown KE & Freeman M (2003) Egfr signalling defines a protective function for ommatidial orientation in the Drosophila eye. Development 130: 5401-12 PubMed GONUTS page
  45. ↑ Gaengel K & Mlodzik M (2003) Egfr signaling regulates ommatidial rotation and cell motility in the Drosophila eye via MAPK/Pnt signaling and the Ras effector Canoe/AF6. Development 130: 5413-23 PubMed GONUTS page
  46. ↑ Baker NE & Yu SY (2001) The EGF receptor defines domains of cell cycle progression and survival to regulate cell number in the developing Drosophila eye. Cell 104: 699-708 PubMed GONUTS page
  47. ↑ Rotoli D et al. (1998) hold up is required for establishment of oocyte positioning, follicle cell fate and egg polarity and cooperates with Egfr during Drosophila oogenesis. Genetics 148: 767-73 PubMed GONUTS page
  48. ↑ 48.0 48.1 Cela C & Llimargas M (2006) Egfr is essential for maintaining epithelial integrity during tracheal remodelling in Drosophila. Development 133: 3115-25 PubMed GONUTS page
  49. ↑ Fulga TA & Rørth P (2002) Invasive cell migration is initiated by guided growth of long cellular extensions. Nat Cell Biol 4: 715-9 PubMed GONUTS page
  50. ↑ Schnorr JD et al. (2001) Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis. Genetics 159: 609-22 PubMed GONUTS page
  51. ↑ Wang H et al. (2006) Rap-GEF signaling controls stem cell anchoring to their niche through regulating DE-cadherin-mediated cell adhesion in the Drosophila testis. Dev Cell 10: 117-26 PubMed GONUTS page
  52. ↑ Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
  53. ↑ Baonza A et al. (2000) DER signaling restricts the boundaries of the wing field during Drosophila development. Proc Natl Acad Sci U S A 97: 7331-5 PubMed GONUTS page
  54. ↑ Lai EC (2002) Developmental signaling: shrimp and strawberries help flies make cones. Curr Biol 12: R722-4 PubMed GONUTS page
  55. ↑ Parker J (2006) Control of compartment size by an EGF ligand from neighboring cells. Curr Biol 16: 2058-65 PubMed GONUTS page
  56. ↑ Cook T (2003) Cell diversity in the retina: more than meets the eye. Bioessays 25: 921-5 PubMed GONUTS page
  57. ↑ Frankfort BJ & Mardon G (2002) R8 development in the Drosophila eye: a paradigm for neural selection and differentiation. Development 129: 1295-306 PubMed GONUTS page
  58. ↑ Zettervall CJ et al. (2004) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci U S A 101: 14192-7 PubMed GONUTS page
  59. ↑ Firth LC & Baker NE (2005) Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye. Dev Cell 8: 541-51 PubMed GONUTS page
  60. ↑ Brachmann CB & Cagan RL (2003) Patterning the fly eye: the role of apoptosis. Trends Genet 19: 91-6 PubMed GONUTS page
  61. ↑ Cordero J et al. (2004) A role for wingless in an early pupal cell death event that contributes to patterning the Drosophila eye. Mech Dev 121: 1523-30 PubMed GONUTS page
  62. ↑ Wahlström G et al. (2006) Drosophila alpha-actinin in ovarian follicle cells is regulated by EGFR and Dpp signalling and required for cytoskeletal remodelling. Mech Dev 123: 801-18 PubMed GONUTS page
  63. ↑ Corl AB et al. (2009) Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors. Cell 137: 949-60 PubMed GONUTS page
  64. ↑ Baker NE et al. (1992) Mutations on the second chromosome affecting the Drosophila eye. J Neurogenet 8: 85-100 PubMed GONUTS page
  65. ↑ Baonza A et al. (2001) A primary role for the epidermal growth factor receptor in ommatidial spacing in the Drosophila eye. Curr Biol 11: 396-404 PubMed GONUTS page
  66. ↑ Figeac N et al. (2010) Drosophila adult muscle precursors form a network of interconnected cells and are specified by the rhomboid-triggered EGF pathway. Development 137: 1965-73 PubMed GONUTS page
  67. ↑ Kerber B et al. (1998) Seven-up, the Drosophila homolog of the COUP-TF orphan receptors, controls cell proliferation in the insect kidney. Genes Dev 12: 1781-6 PubMed GONUTS page
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