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FB:Eaat1
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Eaat1 ( synonyms: AF001784, CG3747, Dglt-1, Dglut-1, Drosophila glutamate transporter-1, EAAT, EAAT1, dEAAT, dEAAT1, dEaat1, excitatory amino acid transporter 1, glutamate transporter, sodium-dependent excitatory amino acid transporter 1, sodium-dependent glutamate transporter, sodium-excitatory-glutamate-cotransporter ) | |
| Protein Name(s) | Excitatory amino acid transporter 1, | |
| External Links | ||
| FB | FBgn0026439 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005313 |
L-glutamate transmembrane transporter activity |
FB:FBrf0103033 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005313 |
L-glutamate transmembrane transporter activity |
FB:FBrf0123076 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005313 |
L-glutamate transmembrane transporter activity |
FB:FBrf0126733 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0106218 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0210975 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006835 |
dicarboxylic acid transport |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007268 |
synaptic transmission |
FB:FBrf0212176 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008340 |
determination of adult lifespan |
FB:FBrf0174487 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008345 |
larval locomotory behavior |
FB:FBrf0212176 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0014853 |
regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction |
FB:FBrf0192197 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0015183 |
L-aspartate transmembrane transporter activity |
FB:FBrf0103033 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0015501 |
glutamate:sodium symporter activity |
FB:FBrf0103033 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0015501 |
glutamate:sodium symporter activity |
FB:FBrf0106218 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0015810 |
aspartate transport |
FB:FBrf0103033 |
IC: Inferred by Curator |
GO:0015183 |
P |
From FB |
||
| GO:0015813 |
L-glutamate transport |
FB:FBrf0103033 |
IC: Inferred by Curator |
GO:0005313 |
P |
From FB |
||
| GO:0015813 |
L-glutamate transport |
FB:FBrf0126733 |
IC: Inferred by Curator |
GO:0005313 |
P |
From FB |
||
| GO:0016021 |
integral to membrane |
FB:FBrf0126733 |
IC: Inferred by Curator |
GO:0005313 |
C |
From FB |
||
| GO:0017153 |
sodium:dicarboxylate symporter activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0043005 |
neuron projection |
FB:FBrf0174487 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0043195 |
terminal button |
FB:FBrf0192197 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
|
colocalizes_with |
GO:0031594 |
neuromuscular junction |
FB:FBrf0192197 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Seal RP et al. (1998) Identification and characterization of a cDNA encoding a neuronal glutamate transporter from Drosophila melanogaster. Receptors Channels 6: 51-64 PubMed GONUTS page
- ↑ Kawano T et al. (1999) Cloning and characterization of a Drosophila melanogaster cDNA encoding a glutamate transporter. Biosci Biotechnol Biochem 63: 2042-4 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Besson MT et al. (2000) Selective high-affinity transport of aspartate by a Drosophila homologue of the excitatory amino-acid transporters. Curr Biol 10: 207-10 PubMed GONUTS page
- ↑ 4.0 4.1 Besson MT et al. (1999) Identification and structural characterization of two genes encoding glutamate transporter homologues differently expressed in the nervous system of Drosophila melanogaster. FEBS Lett 443: 97-104 PubMed GONUTS page
- ↑ 5.0 5.1 Stacey SM et al. (2010) Drosophila glial glutamate transporter Eaat1 is regulated by fringe-mediated notch signaling and is essential for larval locomotion. J Neurosci 30: 14446-57 PubMed GONUTS page
- ↑ 6.0 6.1 Rival T et al. (2004) Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain. Curr Biol 14: 599-605 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Rival T et al. (2006) Physiological requirement for the glutamate transporter dEAAT1 at the adult Drosophila neuromuscular junction. J Neurobiol 66: 1061-74 PubMed GONUTS page
