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FB:E2f2
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | E2f2 ( synonyms: CG1071, E2F, E2F2, dE2F-2, dE2F2, dE2f2, de2f2, e2f2 ) | |
| Protein Name(s) | E2F transcription factor 2, | |
| External Links | ||
| FB | FBgn0024371 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000082 |
G1/S transition of mitotic cell cycle |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0180022 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0180259 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000785 |
chromatin |
FB:FBrf0180022 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007113 |
endomitotic cell cycle |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007310 |
oocyte dorsal/ventral axis specification |
FB:FBrf0145711 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007314 |
oocyte anterior/posterior axis specification |
FB:FBrf0145711 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007444 |
imaginal disc development |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0151952 |
IPI: Inferred from Physical Interaction |
FB:FBgn0038390 |
F |
From FB |
||
| GO:0008156 |
negative regulation of DNA replication |
FB:FBrf0141502 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008156 |
negative regulation of DNA replication |
FB:FBrf0159210 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031523 |
Myb complex |
FB:FBrf0180022 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0031523 |
Myb complex |
FB:FBrf0180259 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0035189 |
Rb-E2F complex |
FB:FBrf0151952 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0042023 |
DNA endoreduplication |
FB:FBrf0161049 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010382 |
P |
From FB |
||
| GO:0042023 |
DNA endoreduplication |
FB:FBrf0161049 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045749 |
negative regulation of S phase of mitotic cell cycle |
FB:FBrf0151952 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
|
contributes_to |
GO:0001078 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription |
FB:FBrf0151952 |
IPI: Inferred from Physical Interaction |
FB:FBgn0038390 |
F |
From FB |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Korenjak M et al. (2004) Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Cell 119: 181-93 PubMed GONUTS page
- ↑ 3.0 3.1 Lewis PW et al. (2004) Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex. Genes Dev 18: 2929-40 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Stevaux O et al. (2002) Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. EMBO J 21: 4927-37 PubMed GONUTS page
- ↑ Cayirlioglu P et al. (2001) Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells. Development 128: 5085-98 PubMed GONUTS page
- ↑ Cayirlioglu P et al. (2003) Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells. Mol Cell Biol 23: 2123-34 PubMed GONUTS page
- ↑ 7.0 7.1 Weng L et al. (2003) Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development. EMBO J 22: 3865-75 PubMed GONUTS page