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FB:E2f2

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) E2f2 ( synonyms: CG1071, E2F, E2F2, dE2F-2, dE2F2, dE2f2, de2f2, e2f2 )
Protein Name(s) E2F transcription factor 2,
External Links
FB FBgn0024371

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000082

G1/S transition of mitotic cell cycle

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0180022
PMID:15479636[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0180259
PMID:15545624[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000785

chromatin

FB:FBrf0180022
PMID:15479636[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0007113

endomitotic cell cycle

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0007310

oocyte dorsal/ventral axis specification

FB:FBrf0145711

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007314

oocyte anterior/posterior axis specification

FB:FBrf0145711

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007444

imaginal disc development

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0008134

transcription factor binding

FB:FBrf0151952
PMID:12234932[4]

IPI: Inferred from Physical Interaction

FB:FBgn0038390

F

From FB

GO:0008156

negative regulation of DNA replication

FB:FBrf0141502
PMID:11748144[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008156

negative regulation of DNA replication

FB:FBrf0159210
PMID:12612083[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031523

Myb complex

FB:FBrf0180022
PMID:15479636[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0031523

Myb complex

FB:FBrf0180259
PMID:15545624[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0035189

Rb-E2F complex

FB:FBrf0151952
PMID:12234932[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0042023

DNA endoreduplication

FB:FBrf0161049
PMID:12881421[7]

IGI: Inferred from Genetic Interaction

FB:FBgn0010382

P

From FB

GO:0042023

DNA endoreduplication

FB:FBrf0161049
PMID:12881421[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045749

negative regulation of S phase of mitotic cell cycle

FB:FBrf0151952
PMID:12234932[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

GO:0048477

oogenesis

FB:FBrf0167269
PMID:14616073[1]

TAS: Traceable Author Statement

P

From FB

contributes_to

GO:0001078

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription

FB:FBrf0151952
PMID:12234932[4]

IPI: Inferred from Physical Interaction

FB:FBgn0038390

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
  2. 2.0 2.1 2.2 Korenjak M et al. (2004) Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Cell 119: 181-93 PubMed GONUTS page
  3. 3.0 3.1 Lewis PW et al. (2004) Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex. Genes Dev 18: 2929-40 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Stevaux O et al. (2002) Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. EMBO J 21: 4927-37 PubMed GONUTS page
  5. Cayirlioglu P et al. (2001) Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells. Development 128: 5085-98 PubMed GONUTS page
  6. Cayirlioglu P et al. (2003) Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells. Mol Cell Biol 23: 2123-34 PubMed GONUTS page
  7. 7.0 7.1 Weng L et al. (2003) Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development. EMBO J 22: 3865-75 PubMed GONUTS page
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