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FB:E2f
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | E2f ( synonyms: CG6376, DRTF1/E2F, DmE2F-1, Dp, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, E2-promoter binding factor, E2F, E2F-1, E2F1, E2f1, Evar(3)164, dE2F, dE2F1, dE2f, dE2f1, de2f1, def21, drosE2F1, e2f, e2f1, l(3)07172, l(3)j3B1, l(3)j3C2, l(3)rM729 ) | |
| Protein Name(s) | E2F transcription factor, | |
| External Links | ||
| FB | FBgn0011766 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000082 |
G1/S transition of mitotic cell cycle |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000083 |
regulation of transcription involved in G1/S phase of mitotic cell cycle |
FB:FBrf0124367 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
FB:FBrf0105315 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
FB:FBrf0151952 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0068617 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0068617 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0068617 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3113 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0087034 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015799 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0201281 |
IPI: Inferred from Physical Interaction |
FB:FBgn0002441 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0201281 |
IPI: Inferred from Physical Interaction |
FB:FBgn0020306 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0068617 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0114665 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0124367 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0007307 |
eggshell chorion gene amplification |
FB:FBrf0161618 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007307 |
eggshell chorion gene amplification |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007444 |
imaginal disc development |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0073014 |
IPI: Inferred from Physical Interaction |
FB:FBgn0011763 |
F |
From FB |
||
| GO:0008134 |
transcription factor binding |
FB:FBrf0151952 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015799 |
F |
From FB |
||
| GO:0008284 |
positive regulation of cell proliferation |
FB:FBrf0136845 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0009987 |
cellular process |
FB:FBrf0175143 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010628 |
positive regulation of gene expression |
FB:FBrf0201281 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0019730 |
antimicrobial humoral response |
FB:FBrf0190362 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035189 |
Rb-E2F complex |
FB:FBrf0087034 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0035189 |
Rb-E2F complex |
FB:FBrf0151952 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0040007 |
growth |
FB:FBrf0124367 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0042023 |
DNA endoreduplication |
FB:FBrf0161049 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010382 |
P |
From FB |
||
| GO:0042023 |
DNA endoreduplication |
FB:FBrf0161049 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045476 |
nurse cell apoptotic process |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045850 |
positive regulation of nurse cell apoptotic process |
FB:FBrf0155518 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0068617 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0105315 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0048666 |
neuron development |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048813 |
dendrite morphogenesis |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051726 |
regulation of cell cycle |
FB:FBrf0096209 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051726 |
regulation of cell cycle |
FB:FBrf0125443 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0060537 |
muscle tissue development |
FB:FBrf0190556 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
contributes_to |
GO:0000981 |
sequence-specific DNA binding RNA polymerase II transcription factor activity |
FB:FBrf0073014 |
IPI: Inferred from Physical Interaction |
FB:FBgn0011763 |
F |
From FB |
|
|
contributes_to |
GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0105315 |
IPI: Inferred from Physical Interaction |
FB:FBgn0011763 |
F |
From FB |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Sawado T et al. (1998) dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster. Biochem Biophys Res Commun 251: 409-15 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Stevaux O et al. (2002) Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. EMBO J 21: 4927-37 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Ohtani K & Nevins JR (1994) Functional properties of a Drosophila homolog of the E2F1 gene. Mol Cell Biol 14: 1603-12 PubMed GONUTS page
- ↑ 5.0 5.1 Du W et al. (1996) RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev 10: 1206-18 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Lu J et al. (2007) A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proc Natl Acad Sci U S A 104: 9381-6 PubMed GONUTS page
- ↑ McNairn AJ & Gilbert DM (2003) Epigenomic replication: linking epigenetics to DNA replication. Bioessays 25: 647-56 PubMed GONUTS page
- ↑ 8.0 8.1 Dynlacht BD et al. (1994) DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc Natl Acad Sci U S A 91: 6359-63 PubMed GONUTS page
- ↑ Potter CJ & Xu T (2001) Mechanisms of size control. Curr Opin Genet Dev 11: 279-86 PubMed GONUTS page
- ↑ Boutros M et al. (2004) Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303: 832-5 PubMed GONUTS page
- ↑ Kleino A et al. (2005) Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway. EMBO J 24: 3423-34 PubMed GONUTS page
- ↑ 12.0 12.1 Weng L et al. (2003) Critical role of active repression by E2F and Rb proteins in endoreplication during Drosophila development. EMBO J 22: 3865-75 PubMed GONUTS page
- ↑ Royzman I et al. (2002) The E2F cell cycle regulator is required for Drosophila nurse cell DNA replication and apoptosis. Mech Dev 119: 225-37 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
- ↑ Royzman I et al. (1997) Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program. Genes Dev 11: 1999-2011 PubMed GONUTS page
- ↑ Weinkove D & Leevers SJ (2000) The genetic control of organ growth: insights from Drosophila. Curr Opin Genet Dev 10: 75-80 PubMed GONUTS page
