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FB:E(bx)

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) E(bx) ( synonyms: CG10894, CG17135, CG32346, CG32478, CG7022, E(BX), E(Bx), En-bx, NURF, NURF-215, NURF-301, NURF215, NURF301, NuRF301, Nucleosome remodeling factor, Nucleosome remodeling factor - 215kD, Nurf 301, Nurf-215, Nurf301, dNURF, dNURF301, l(3)122, l(3)ry122, nucleosome remodeling factor, nucleosome-remodeling factor, nurf301, p215, p301 )
Protein Name(s) Enhancer of bithorax,
External Links
FB FBgn0000541

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR017956

F

From FB

GO:0006325

chromatin organization

FB:FBrf0201334
PMID:17507677[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006334

nucleosome assembly

FB:FBrf0140787

NAS: Non-traceable Author Statement

P

From FB

GO:0006338

chromatin remodeling

FB:FBrf0155786
PMID:12502740[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006351

transcription, DNA-dependent

FB:FBrf0135834
PMID:11279013[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0006351

transcription, DNA-dependent

FB:FBrf0155786
PMID:12502740[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007095

mitotic cell cycle G2/M transition DNA damage checkpoint

FB:FBrf0212700
PMID:21205937[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0261530

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001965

F

From FB

GO:0016589

NURF complex

FB:FBrf0139755
PMID:11583616[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0016589

NURF complex

FB:FBrf0140787

NAS: Non-traceable Author Statement

C

From FB

GO:0016589

NURF complex

FB:FBrf0155786
PMID:12502740[2]

TAS: Traceable Author Statement

C

From FB

GO:0016922

ligand-dependent nuclear receptor binding

FB:FBrf0190536
PMID:16264191[6]

IPI: Inferred from Physical Interaction

FB:FBgn0000546

F

From FB

GO:0030097

hemopoiesis

FB:FBrf0155786
PMID:12502740[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035073

pupariation

FB:FBrf0190536
PMID:16264191[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035076

ecdysone receptor-mediated signaling pathway

FB:FBrf0190536
PMID:16264191[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0000546

P

From FB

GO:0042766

nucleosome mobilization

FB:FBrf0108784
PMID:10399912[7]

IDA: Inferred from Direct Assay

P

From FB

GO:0042766

nucleosome mobilization

FB:FBrf0139755
PMID:11583616[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0042766

nucleosome mobilization

FB:FBrf0173283
PMID:14635254[8]

TAS: Traceable Author Statement

P

From FB

GO:0045747

positive regulation of Notch signaling pathway

FB:FBrf0211977
PMID:20685964[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0004647

P

From FB

GO:0045747

positive regulation of Notch signaling pathway

FB:FBrf0211977
PMID:20685964[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046331

lateral inhibition

FB:FBrf0214518

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[10]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Bai X et al. (2007) Regional control of chromatin organization by noncoding roX RNAs and the NURF remodeling complex in Drosophila melanogaster. Genetics 176: 1491-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Badenhorst P et al. (2002) Biological functions of the ISWI chromatin remodeling complex NURF. Genes Dev 16: 3186-98 PubMed GONUTS page
  3. Mizuguchi G et al. (2001) ATP-dependent nucleosome remodeling and histone hyperacetylation synergistically facilitate transcription of chromatin. J Biol Chem 276: 14773-83 PubMed GONUTS page
  4. Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
  5. 5.0 5.1 Xiao H et al. (2001) Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions. Mol Cell 8: 531-43 PubMed GONUTS page
  6. 6.0 6.1 6.2 Badenhorst P et al. (2005) The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis. Genes Dev 19: 2540-5 PubMed GONUTS page
  7. Hamiche A et al. (1999) ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF. Cell 97: 833-42 PubMed GONUTS page
  8. Lusser A & Kadonaga JT (2003) Chromatin remodeling by ATP-dependent molecular machines. Bioessays 25: 1192-200 PubMed GONUTS page
  9. 9.0 9.1 Kugler SJ & Nagel AC (2010) A novel Pzg-NURF complex regulates Notch target gene activity. Mol Biol Cell 21: 3443-8 PubMed GONUTS page
  10. Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
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