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FB:Dys
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Dys ( synonyms: CG17750, CG31175, CG34157, CG7240, CG7243, CG7344, DLP, DLP1, DLP186, DLP2, DLP3, DmDLP, DmDYS, Dp117, Dp186, Dp205, Dystrophin Dp186, Dystrophin-like protein 1, Dystrophin-like protein 186, Dystrophin-like protein 2, Dystrophin-like protein 3, GI3046716, IDLP, det, detached, dmDLP, dmDp186, dmDys, dys, dystrophin ) | |
| Protein Name(s) | Dystrophin, | |
| External Links | ||
| FB | FBgn0260003 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003779 |
actin binding |
FB:FBrf0152121 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0178372 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003779 |
actin binding |
FB:FBrf0178373 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005198 |
structural molecule activity |
FB:FBrf0129830 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005200 |
structural constituent of cytoskeleton |
FB:FBrf0178372 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005200 |
structural constituent of cytoskeleton |
FB:FBrf0178373 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005509 |
calcium ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005856 |
cytoskeleton |
FB:FBrf0129830 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005856 |
cytoskeleton |
FB:FBrf0178372 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005856 |
cytoskeleton |
FB:FBrf0178373 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0007274 |
neuromuscular synaptic transmission |
FB:FBrf0191057 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0007474 |
imaginal disc-derived wing vein specification |
FB:FBrf0203132 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007517 |
muscle organ development |
FB:FBrf0178372 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007517 |
muscle organ development |
FB:FBrf0178373 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0008092 |
cytoskeletal protein binding |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008307 |
structural constituent of muscle |
FB:FBrf0129834 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:12635 |
F |
From FB |
||
| GO:0008307 |
structural constituent of muscle |
FB:FBrf0129834 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:2928 |
F |
From FB |
||
| GO:0008307 |
structural constituent of muscle |
FB:FBrf0129834 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3032 |
F |
From FB |
||
| GO:0008307 |
structural constituent of muscle |
FB:FBrf0178372 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0008307 |
structural constituent of muscle |
FB:FBrf0178373 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0008586 |
imaginal disc-derived wing vein morphogenesis |
FB:FBrf0076146 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008586 |
imaginal disc-derived wing vein morphogenesis |
FB:FBrf0212767 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0129834 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:12635 |
C |
From FB |
||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0129834 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:2928 |
C |
From FB |
||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0129834 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:3032 |
C |
From FB |
||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0130697 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0132100 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0178372 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0178373 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0191923 |
IPI: Inferred from Physical Interaction |
FB:FBgn0034072 |
C |
From FB |
||
| GO:0030010 |
establishment of cell polarity |
FB:FBrf0192541 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046716 |
muscle cell homeostasis |
FB:FBrf0192541 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046928 |
regulation of neurotransmitter secretion |
FB:FBrf0204668 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0048172 |
regulation of short-term neuronal synaptic plasticity |
FB:FBrf0191057 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0050699 |
WW domain binding |
FB:FBrf0192541 |
IPI: Inferred from Physical Interaction |
FB:FBgn0034072 |
F |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Röper K et al. (2002) The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families. J Cell Sci 115: 4215-25 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
- ↑ 3.0 3.1 van der Plas MC et al. (2006) Dystrophin is required for appropriate retrograde control of neurotransmitter release at the Drosophila neuromuscular junction. J Neurosci 26: 333-44 PubMed GONUTS page
- ↑ Christoforou CP et al. (2008) The detached locus encodes Drosophila Dystrophin, which acts with other components of the Dystrophin Associated Protein Complex to influence intercellular signalling in developing wing veins. Dev Biol 313: 519-32 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Greener MJ & Roberts RG (2000) Conservation of components of the dystrophin complex in Drosophila. FEBS Lett 482: 13-8 PubMed GONUTS page
- ↑ Sturtevant MA & Bier E (1995) Analysis of the genetic hierarchy guiding wing vein development in Drosophila. Development 121: 785-801 PubMed GONUTS page
- ↑ Pilgram GS et al. (2011) The RhoGAP crossveinless-c interacts with Dystrophin and is required for synaptic homeostasis at the Drosophila neuromuscular junction. J Neurosci 31: 492-500 PubMed GONUTS page
- ↑ Yatsenko AS et al. (2007) A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila. J Biol Chem 282: 15159-69 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Shcherbata HR et al. (2007) Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy. EMBO J 26: 481-93 PubMed GONUTS page
- ↑ Fradkin LG et al. (2008) The dystrophin Dp186 isoform regulates neurotransmitter release at a central synapse in Drosophila. J Neurosci 28: 5105-14 PubMed GONUTS page