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FB:Duox

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Duox ( synonyms: CG3131, DUOX, dDuox )
Protein Name(s) Dual oxidase,
External Links
FB FBgn0031464

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002385

mucosal immune response

FB:FBrf0207552
PMID:19289084[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0002385

mucosal immune response

FB:FBrf0208708
PMID:19668222[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004601

peroxidase activity

FB:FBrf0190609
PMID:16272120[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0005509

calcium ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002048
InterPro:IPR011992

F

From FB

GO:0006979

response to oxidative stress

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002007
InterPro:IPR010255
InterPro:IPR019791

P

From FB

GO:0008365

adult chitin-based cuticle development

FB:FBrf0215569
PMID:21808060[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009055

electron carrier activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

F

From FB

GO:0016021

integral to membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

C

From FB

GO:0016175

superoxide-generating NADPH oxidase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:AF123275

F

From FB

GO:0020037

heme binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002007
InterPro:IPR010255
InterPro:IPR019791

F

From FB

GO:0035220

wing disc development

FB:FBrf0215569
PMID:21808060[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042742

defense response to bacterium

FB:FBrf0190609
PMID:16272120[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043066

negative regulation of apoptotic process

FB:FBrf0215569
PMID:21808060[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048085

adult chitin-containing cuticle pigmentation

FB:FBrf0215569
PMID:21808060[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050660

flavin adenine dinucleotide binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

F

From FB

GO:0055114

oxidation-reduction process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002007
InterPro:IPR010255
InterPro:IPR013112
InterPro:IPR013121
InterPro:IPR017927
InterPro:IPR017938
InterPro:IPR019791

P

From FB

GO:0072593

reactive oxygen species metabolic process

FB:FBrf0215569
PMID:21808060[4]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Ha EM et al. (2009) Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity. Dev Cell 16: 386-97 PubMed GONUTS page
  2. Ha EM et al. (2009) Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut. Nat Immunol 10: 949-57 PubMed GONUTS page
  3. 3.0 3.1 Ha EM et al. (2005) A direct role for dual oxidase in Drosophila gut immunity. Science 310: 847-50 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Anh NT et al. (2011) Essential role of Duox in stabilization of Drosophila wing. J Biol Chem 286: 33244-51 PubMed GONUTS page
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