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FB:Drs

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Drs ( synonyms: BcDNA:LP03851, CG10810, Crp, Cysteine-rich-protein, DIM 19, DRO, DROM, DRS, Drm, Drom, Dros, Droso, Drosomcycin, Drosomycin precursor, Drosomyocin, Drosophila Immune induced molecule 19, cysteine-rich peptide, dmy1, drm, drom, drosomyci, drosomycin, drs, drsm )
Protein Name(s) Drosomycin,
External Links
FB FBgn0010381

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005576

extracellular region

FB:FBrf0104525
PMID:9736738[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0006952

defense response

FB:FBrf0104525
PMID:9736738[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0019731

antibacterial humoral response

FB:FBrf0174342
PMID:15032585[2]

TAS: Traceable Author Statement

P

From FB

GO:0019732

antifungal humoral response

FB:FBrf0100121
PMID:9405661[3]

IEP: Inferred from Expression Pattern

P

From FB

GO:0019732

antifungal humoral response

FB:FBrf0124009

NAS: Non-traceable Author Statement

P

From FB

GO:0019732

antifungal humoral response

FB:FBrf0174342
PMID:15032585[2]

TAS: Traceable Author Statement

P

From FB

GO:0045087

innate immune response

FB:FBrf0188361
PMID:15797611[4]

NAS: Non-traceable Author Statement

P

From FB

GO:0050829

defense response to Gram-negative bacterium

FB:FBrf0174342
PMID:15032585[2]

TAS: Traceable Author Statement

P

From FB

GO:0050832

defense response to fungus

FB:FBrf0076717
PMID:7806546[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0050832

defense response to fungus

FB:FBrf0076717
PMID:7806546[5]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0050832

defense response to fungus

FB:FBrf0084126
PMID:7588819[6]

IDA: Inferred from Direct Assay

P

From FB

GO:0050832

defense response to fungus

FB:FBrf0127230
PMID:10793472[7]

TAS: Traceable Author Statement

P

From FB

GO:0050832

defense response to fungus

FB:FBrf0141068
PMID:11283698[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0050832

defense response to fungus

FB:FBrf0144920
PMID:11869341[9]

TAS: Traceable Author Statement

P

From FB

GO:0050832

defense response to fungus

FB:FBrf0155688
PMID:12530956[10]

TAS: Traceable Author Statement

P

From FB

GO:0050832

defense response to fungus

FB:FBrf0193399
PMID:16824706[11]

IDA: Inferred from Direct Assay

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Uttenweiler-Joseph S et al. (1998) Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study. Proc Natl Acad Sci U S A 95: 11342-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 Brennan CA & Anderson KV (2004) Drosophila: the genetics of innate immune recognition and response. Annu Rev Immunol 22: 457-83 PubMed GONUTS page
  3. Lemaitre B et al. (1997) Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc Natl Acad Sci U S A 94: 14614-9 PubMed GONUTS page
  4. Kwiatkowski DP (2005) The complexity of genetic variation in a simple immune system. Trends Genet 21: 197-9 PubMed GONUTS page
  5. 5.0 5.1 Fehlbaum P et al. (1994) Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides. J Biol Chem 269: 33159-63 PubMed GONUTS page
  6. Levashina EA et al. (1995) Metchnikowin, a novel immune-inducible proline-rich peptide from Drosophila with antibacterial and antifungal properties. Eur J Biochem 233: 694-700 PubMed GONUTS page
  7. Meister M et al. (2000) The antimicrobial host defense of Drosophila. Curr Top Microbiol Immunol 248: 17-36 PubMed GONUTS page
  8. Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
  9. Chapman T (2001) Seminal fluid-mediated fitness traits in Drosophila. Heredity (Edinb) 87: 511-21 PubMed GONUTS page
  10. Silverman N (2003) Flies kNOw how to signal. Dev Cell 4: 5-6 PubMed GONUTS page
  11. Yang WY et al. (2006) Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster. Gene 379: 26-32 PubMed GONUTS page
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