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FB:Drp1

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Drp1 ( synonyms: CG3210, DRP1, Dnm1/Drp1, Drp, Drp-1, drp-1, drp1, dynamin related protein-1, dynamin-2, dynamin-related protein, frat, fratboy, l(2)22Fc, l(2)22Fd, l(2)ND2, l(2)ND3, lethal(2)22Fc, lethal(2)22Fd, near dpp complementation group 2, near dpp complementation group 3, noodle )
Protein Name(s) Dynamin related protein 1,
External Links
FB FBgn0026479

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000910

cytokinesis

FB:FBrf0180064
PMID:15380073[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003924

GTPase activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001401
InterPro:IPR003130

F

From FB

GO:0005525

GTP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000375
InterPro:IPR001401
InterPro:IPR003130

F

From FB

GO:0005875

microtubule associated complex

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:AF019043

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0108045
PMID:10201074[2]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0204649
PMID:18433294[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0007005

mitochondrion organization

FB:FBrf0183138

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007005

mitochondrion organization

FB:FBrf0206104
PMID:18799731[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007005

mitochondrion organization

FB:FBrf0213174
PMID:21274005[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016050

vesicle organization

FB:FBrf0183138

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016185

synaptic vesicle budding from presynaptic membrane

FB:FBrf0127207
PMID:10798391[6]

NAS: Non-traceable Author Statement

P

From FB

GO:0030382

sperm mitochondrion organization

FB:FBrf0200064
PMID:18690063[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048312

intracellular distribution of mitochondria

FB:FBrf0183138

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051646

mitochondrion localization

FB:FBrf0188182
PMID:16055061[8]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Echard A et al. (2004) Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol 14: 1685-93 PubMed GONUTS page
  2. van der Bliek AM (1999) Functional diversity in the dynamin family. Trends Cell Biol 9: 96-102 PubMed GONUTS page
  3. Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
  4. Deng H et al. (2008) The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc Natl Acad Sci U S A 105: 14503-8 PubMed GONUTS page
  5. Rival T et al. (2011) Inner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways. EMBO Rep 12: 223-30 PubMed GONUTS page
  6. Lloyd TE et al. (2000) A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron 26: 45-50 PubMed GONUTS page
  7. Aldridge AC et al. (2007) Roles for Drp1, a dynamin-related protein, and milton, a kinesin-associated protein, in mitochondrial segregation, unfurling and elongation during Drosophila spermatogenesis. Fly (Austin) 1: 38-46 PubMed GONUTS page
  8. Verstreken P et al. (2005) Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron 47: 365-78 PubMed GONUTS page
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