GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:Dredd
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Dredd ( synonyms: CG7486, Ced-3-like/Nedd2-like protein, DCP-2, DCP-2/DREDD, DCP2, DREDD, Dcp-2, Dcp-2/Dredd, Dcp2, Death caspase-2, Dedd, Dredd/DCP-2, Drosophila caspase, EG:115C2.9, Redd, anon-1BCa, caspase, dcp-2/dredd, dredd ) | |
| Protein Name(s) | Death related ced-3/Nedd2-like protein, | |
| External Links | ||
| FB | FBgn0020381 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004175 |
endopeptidase activity |
FB:FBrf0208153 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0104738 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:1500 |
F |
From FB |
||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0104738 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:1509 |
F |
From FB |
||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0111320 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0113775 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0116345 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0132215 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0134503 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0149068 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0004197 |
cysteine-type endopeptidase activity |
FB:FBrf0156100 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0129865 |
IPI: Inferred from Physical Interaction |
FB:FBgn0038928 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0133276 |
IPI: Inferred from Physical Interaction |
FB:FBgn0014018 |
F |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0104738 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006508 |
proteolysis |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR001309 |
P |
From FB |
||
| GO:0006915 |
apoptotic process |
FB:FBrf0104738 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0104738 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0011706 |
P |
From FB |
||
| GO:0006915 |
apoptotic process |
FB:FBrf0113775 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0134503 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0141068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0149068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006915 |
apoptotic process |
FB:FBrf0173268 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0128454 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006955 |
immune response |
FB:FBrf0141068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006955 |
immune response |
FB:FBrf0193652 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006963 |
positive regulation of antibacterial peptide biosynthetic process |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006963 |
positive regulation of antibacterial peptide biosynthetic process |
FB:FBrf0134503 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006963 |
positive regulation of antibacterial peptide biosynthetic process |
FB:FBrf0149068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007291 |
sperm individualization |
FB:FBrf0167989 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016485 |
protein processing |
FB:FBrf0208153 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0016505 |
apoptotic protease activator activity |
FB:FBrf0104738 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0045087 |
innate immune response |
FB:FBrf0134503 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048935 |
peripheral nervous system neuron development |
FB:FBrf0210269 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050829 |
defense response to Gram-negative bacterium |
FB:FBrf0133276 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050829 |
defense response to Gram-negative bacterium |
FB:FBrf0179043 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0061057 |
peptidoglycan recognition protein signaling pathway |
FB:FBrf0133276 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ertürk-Hasdemir D et al. (2009) Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes. Proc Natl Acad Sci U S A 106: 9779-84 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Chen P et al. (1998) Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila. Dev Biol 201: 202-16 PubMed GONUTS page
- ↑ Abrams JM (1999) An emerging blueprint for apoptosis in Drosophila. Trends Cell Biol 9: 435-40 PubMed GONUTS page
- ↑ Tittel JN & Steller H (2000) A comparison of programmed cell death between species. Genome Biol 1: REVIEWS0003 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Kumar S & Doumanis J (2000) The fly caspases. Cell Death Differ 7: 1039-44 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Richardson H & Kumar S (2002) Death to flies: Drosophila as a model system to study programmed cell death. J Immunol Methods 265: 21-38 PubMed GONUTS page
- ↑ Brachmann CB & Cagan RL (2003) Patterning the fly eye: the role of apoptosis. Trends Genet 19: 91-6 PubMed GONUTS page
- ↑ Hu S & Yang X (2000) dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD. J Biol Chem 275: 30761-4 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Leulier F et al. (2000) The Drosophila caspase Dredd is required to resist gram-negative bacterial infection. EMBO Rep 1: 353-8 PubMed GONUTS page
- ↑ 10.0 10.1 Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
- ↑ Lawen A (2003) Apoptosis-an introduction. Bioessays 25: 888-96 PubMed GONUTS page
- ↑ Elrod-Erickson M et al. (2000) Interactions between the cellular and humoral immune responses in Drosophila. Curr Biol 10: 781-4 PubMed GONUTS page
- ↑ Ryu JH et al. (2006) An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity. EMBO J 25: 3693-701 PubMed GONUTS page
- ↑ Huh JR et al. (2004) Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. PLoS Biol 2: E15 PubMed GONUTS page
- ↑ Ayyar S et al. (2007) NF-kappaB/Rel-mediated regulation of the neural fate in Drosophila. PLoS One 2: e1178 PubMed GONUTS page
- ↑ Leclerc V & Reichhart JM (2004) The immune response of Drosophila melanogaster. Immunol Rev 198: 59-71 PubMed GONUTS page
acd |
eip |
p cont.s |
