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FB:Dp
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Dp ( synonyms: 49Fk, CG4654, DDP1, DP, DP1, DmDP, Dp1, TFPD2, dDP, dDP1, dDp, dimerization partner, dp, l(2)49Fk, l(2)vr10, lethal(2)49Fk, vr10 ) | |
| Protein Name(s) | DP transcription factor, | |
| External Links | ||
| FB | FBgn0011763 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
FB:FBrf0073014 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0124295 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0087034 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015799 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0113492 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0124295 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
FB:FBrf0124295 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007049 |
cell cycle |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007113 |
endomitotic cell cycle |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007307 |
eggshell chorion gene amplification |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008069 |
dorsal/ventral axis specification, ovarian follicular epithelium |
FB:FBrf0128583 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0073014 |
IPI: Inferred from Physical Interaction |
FB:FBgn0011766 |
F |
From FB |
||
| GO:0008134 |
transcription factor binding |
FB:FBrf0151952 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015799 |
F |
From FB |
||
| GO:0008134 |
transcription factor binding |
FB:FBrf0151952 |
IPI: Inferred from Physical Interaction |
FB:FBgn0038390 |
F |
From FB |
||
| GO:0008630 |
DNA damage response, signal transduction resulting in induction of apoptosis |
FB:FBrf0205772 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010628 |
positive regulation of gene expression |
FB:FBrf0201281 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031523 |
Myb complex |
FB:FBrf0180022 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0031523 |
Myb complex |
FB:FBrf0180259 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0035189 |
Rb-E2F complex |
FB:FBrf0087034 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045476 |
nurse cell apoptotic process |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045850 |
positive regulation of nurse cell apoptotic process |
FB:FBrf0155518 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0128583 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051726 |
regulation of cell cycle |
FB:FBrf0096209 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051726 |
regulation of cell cycle |
FB:FBrf0125443 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0051726 |
regulation of cell cycle |
FB:FBrf0128583 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
contributes_to |
GO:0000981 |
sequence-specific DNA binding RNA polymerase II transcription factor activity |
FB:FBrf0073014 |
IPI: Inferred from Physical Interaction |
FB:FBgn0011766 |
F |
From FB |
|
|
contributes_to |
GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0105315 |
IPI: Inferred from Physical Interaction |
FB:FBgn0011766 |
F |
From FB |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Dynlacht BD et al. (1994) DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc Natl Acad Sci U S A 91: 6359-63 PubMed GONUTS page
- ↑ 2.0 2.1 Du W et al. (1996) RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. Genes Dev 10: 1206-18 PubMed GONUTS page
- ↑ Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Myster DL et al. (2000) A role for the DP subunit of the E2F transcription factor in axis determination during Drosophila oogenesis. Development 127: 3249-61 PubMed GONUTS page
- ↑ 6.0 6.1 Stevaux O et al. (2002) Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2. EMBO J 21: 4927-37 PubMed GONUTS page
- ↑ Moon NS et al. (2008) E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage. PLoS Genet 4: e1000153 PubMed GONUTS page
- ↑ Lu J et al. (2007) A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proc Natl Acad Sci U S A 104: 9381-6 PubMed GONUTS page
- ↑ Korenjak M et al. (2004) Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes. Cell 119: 181-93 PubMed GONUTS page
- ↑ Lewis PW et al. (2004) Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex. Genes Dev 18: 2929-40 PubMed GONUTS page
- ↑ Royzman I et al. (2002) The E2F cell cycle regulator is required for Drosophila nurse cell DNA replication and apoptosis. Mech Dev 119: 225-37 PubMed GONUTS page
- ↑ Royzman I et al. (1997) Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional program. Genes Dev 11: 1999-2011 PubMed GONUTS page
- ↑ Weinkove D & Leevers SJ (2000) The genetic control of organ growth: insights from Drosophila. Curr Opin Genet Dev 10: 75-80 PubMed GONUTS page
- ↑ Sawado T et al. (1998) dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster. Biochem Biophys Res Commun 251: 409-15 PubMed GONUTS page
