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FB:Doa

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) Doa ( synonyms: CG1658, CG31049, CG33204, CG33553, CG42320, DOA, DOA/CLK2, Mosaic suppressor, Msu, doa, l(3)01705 )
Protein Name(s) Darkener of apricot,
External Links
FB FBgn0259220

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000381

regulation of alternative nuclear mRNA splicing, via spliceosome

FB:FBrf0180650
PMID:15492211[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001964

startle response

FB:FBrf0205756
PMID:18713854[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004672

protein kinase activity

FB:FBrf0074875
PMID:7926721[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0004672

protein kinase activity

FB:FBrf0129982
PMID:10908584[4]

ISS: Inferred from Sequence or Structural Similarity

NCBI_NP:003984

F

From FB

GO:0004672

protein kinase activity

FB:FBrf0202595
PMID:17828581[5]

IDA: Inferred from Direct Assay

F

From FB

GO:0004672

protein kinase activity

FB:FBrf0209673
PMID:19841092[6]

IDA: Inferred from Direct Assay

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0105811
PMID:9885562[7]

IDA: Inferred from Direct Assay

F

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0132098
PMID:10908587[8]

NAS: Non-traceable Author Statement

F

From FB

GO:0004712

protein serine/threonine/tyrosine kinase activity

FB:FBrf0124103

NAS: Non-traceable Author Statement

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290
InterPro:IPR017441

F

From FB

GO:0005634

nucleus

FB:FBrf0079049

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0130184
PMID:11014821[9]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0180650
PMID:15492211[1]

IC: Inferred by Curator

GO:0000381

C

From FB

GO:0005737

cytoplasm

FB:FBrf0130184
PMID:11014821[9]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0202595
PMID:17828581[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005783

endoplasmic reticulum

FB:FBrf0191232
PMID:16452979[10]

IDA: Inferred from Direct Assay

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0204649
PMID:18433294[11]

IDA: Inferred from Direct Assay

C

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0007350

blastoderm segmentation

FB:FBrf0074875
PMID:7926721[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007350

blastoderm segmentation

FB:FBrf0124103

NAS: Non-traceable Author Statement

P

From FB

GO:0007399

nervous system development

FB:FBrf0074875
PMID:7926721[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007399

nervous system development

FB:FBrf0124103

NAS: Non-traceable Author Statement

P

From FB

GO:0007417

central nervous system development

FB:FBrf0079049

NAS: Non-traceable Author Statement

P

From FB

GO:0007548

sex differentiation

FB:FBrf0105811
PMID:9885562[7]

IGI: Inferred from Genetic Interaction

FB:FBgn0003741

P

From FB

GO:0007548

sex differentiation

FB:FBrf0105811
PMID:9885562[7]

IGI: Inferred from Genetic Interaction

FB:FBgn0003742

P

From FB

GO:0007548

sex differentiation

FB:FBrf0105811
PMID:9885562[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008362

chitin-based embryonic cuticle biosynthetic process

FB:FBrf0079049

NAS: Non-traceable Author Statement

P

From FB

GO:0008407

chaeta morphogenesis

FB:FBrf0124103

NAS: Non-traceable Author Statement

P

From FB

GO:0009306

protein secretion

FB:FBrf0191232
PMID:16452979[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030717

karyosome formation

FB:FBrf0162144
PMID:12930750[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031987

locomotion involved in locomotory behavior

FB:FBrf0205756
PMID:18713854[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035071

salivary gland cell autophagic cell death

FB:FBrf0158811
PMID:12593804[13]

IEP: Inferred from Expression Pattern

P

From FB

GO:0042051

compound eye photoreceptor development

FB:FBrf0124103

NAS: Non-traceable Author Statement

P

From FB

GO:0042051

compound eye photoreceptor development

FB:FBrf0130184
PMID:11014821[9]

IEP: Inferred from Expression Pattern

P

From FB

GO:0042051

compound eye photoreceptor development

FB:FBrf0130184
PMID:11014821[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045494

photoreceptor cell maintenance

FB:FBrf0079049

NAS: Non-traceable Author Statement

P

From FB

GO:0046777

protein autophosphorylation

FB:FBrf0074875
PMID:7926721[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0048102

autophagic cell death

FB:FBrf0158811
PMID:12593804[13]

IEP: Inferred from Expression Pattern

P

From FB

GO:0048477

oogenesis

FB:FBrf0079049

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048477

oogenesis

FB:FBrf0162144
PMID:12930750[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0074875
PMID:7926721[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0124103

NAS: Non-traceable Author Statement

P

From FB

GO:0048854

brain morphogenesis

FB:FBrf0205756
PMID:18713854[2]

IMP: Inferred from Mutant Phenotype

P

From FB

NOT

GO:0000165

MAPK cascade

FB:FBrf0130184
PMID:11014821[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0003256

P

From FB

NOT

GO:0000165

MAPK cascade

FB:FBrf0130184
PMID:11014821[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0003366

P

From FB

NOT

GO:0000165

MAPK cascade

FB:FBrf0130184
PMID:11014821[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0003410

P

From FB

NOT

GO:0000165

MAPK cascade

FB:FBrf0130184
PMID:11014821[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0003651

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Park JW et al. (2004) Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci U S A 101: 15974-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 Yamamoto A et al. (2008) Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proc Natl Acad Sci U S A 105: 12393-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Yun B et al. (1994) The Doa locus encodes a member of a new protein kinase family and is essential for eye and embryonic development in Drosophila melanogaster. Genes Dev 8: 1160-73 PubMed GONUTS page
  4. Mount SM & Salz HK (2000) Pre-messenger RNA processing factors in the Drosophila genome. J Cell Biol 150: F37-44 PubMed GONUTS page
  5. 5.0 5.1 Wan Y et al. (2008) DX16 is a novel SR protein phosphorylated by DOA. Mol Cell Biochem 307: 177-83 PubMed GONUTS page
  6. Fan Y et al. (2010) Drosophila translational elongation factor-1gamma is modified in response to DOA kinase activity and is essential for cellular viability. Genetics 184: 141-54 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 Du C et al. (1998) Protein phosphorylation plays an essential role in the regulation of alternative splicing and sex determination in Drosophila. Mol Cell 2: 741-50 PubMed GONUTS page
  8. 8.0 8.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  9. 9.0 9.1 9.2 9.3 9.4 9.5 9.6 9.7 Yun B et al. (2000) The LAMMER protein kinase encoded by the Doa locus of Drosophila is required in both somatic and germline cells and is expressed as both nuclear and cytoplasmic isoforms throughout development. Genetics 156: 749-61 PubMed GONUTS page
  10. 10.0 10.1 Bard F et al. (2006) Functional genomics reveals genes involved in protein secretion and Golgi organization. Nature 439: 604-7 PubMed GONUTS page
  11. Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
  12. 12.0 12.1 Morris JZ et al. (2003) Identification and analysis of mutations in bob, Doa and eight new genes required for oocyte specification and development in Drosophila melanogaster. Genetics 164: 1435-46 PubMed GONUTS page
  13. 13.0 13.1 Gorski SM et al. (2003) A SAGE approach to discovery of genes involved in autophagic cell death. Curr Biol 13: 358-63 PubMed GONUTS page
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