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FB:Dg
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Dg ( synonyms: CG18250, CT41273, DG, DmDG, atsugari, atu, dg, dgn, dys, dystroglycan, dystroglycan-like ) | |
| Protein Name(s) | Dystroglycan, | |
| External Links | ||
| FB | FBgn0034072 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005509 |
calcium ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0192541 |
IPI: Inferred from Physical Interaction |
FB:FBgn0260003 |
F |
From FB |
||
| GO:0007016 |
cytoskeletal anchoring at plasma membrane |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0007163 |
establishment or maintenance of cell polarity |
FB:FBrf0191923 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007295 |
growth of a germarium-derived egg chamber |
FB:FBrf0191923 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007309 |
oocyte axis specification |
FB:FBrf0193906 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007314 |
oocyte anterior/posterior axis specification |
FB:FBrf0151949 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0192541 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010583 |
P |
From FB |
||
| GO:0007474 |
imaginal disc-derived wing vein specification |
FB:FBrf0203132 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008307 |
structural constituent of muscle |
FB:FBrf0129834 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:2666 |
F |
From FB |
||
| GO:0009925 |
basal plasma membrane |
FB:FBrf0191923 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016010 |
dystrophin-associated glycoprotein complex |
FB:FBrf0191923 |
IPI: Inferred from Physical Interaction |
FB:FBgn0260003 |
C |
From FB |
||
| GO:0016011 |
dystroglycan complex |
FB:FBrf0129834 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:2666 |
C |
From FB |
||
| GO:0016011 |
dystroglycan complex |
FB:FBrf0129868 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0016011 |
dystroglycan complex |
FB:FBrf0130696 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0016011 |
dystroglycan complex |
FB:FBrf0137232 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0016203 |
muscle attachment |
FB:FBrf0204214 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016334 |
establishment or maintenance of polarity of follicular epithelium |
FB:FBrf0151949 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030010 |
establishment of cell polarity |
FB:FBrf0192541 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030315 |
T-tubule |
FB:FBrf0204214 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0031594 |
neuromuscular junction |
FB:FBrf0210237 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0035088 |
establishment or maintenance of apical/basal cell polarity |
FB:FBrf0193906 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045197 |
establishment or maintenance of epithelial cell apical/basal polarity |
FB:FBrf0151949 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045197 |
establishment or maintenance of epithelial cell apical/basal polarity |
FB:FBrf0191923 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045214 |
sarcomere organization |
FB:FBrf0204214 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046716 |
muscle cell homeostasis |
FB:FBrf0192541 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046716 |
muscle cell homeostasis |
FB:FBrf0204214 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0060025 |
regulation of synaptic activity |
FB:FBrf0204279 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Shcherbata HR et al. (2007) Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy. EMBO J 26: 481-93 PubMed GONUTS page
- ↑ 2.0 2.1 Hynes RO & Zhao Q (2000) The evolution of cell adhesion. J Cell Biol 150: F89-96 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Yatsenko AS et al. (2007) A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila. J Biol Chem 282: 15159-69 PubMed GONUTS page
- ↑ 4.0 4.1 Poulton JS & Deng WM (2006) Dystroglycan down-regulation links EGF receptor signaling and anterior-posterior polarity formation in the Drosophila oocyte. Proc Natl Acad Sci U S A 103: 12775-80 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Deng WM et al. (2003) Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila. Development 130: 173-84 PubMed GONUTS page
- ↑ Christoforou CP et al. (2008) The detached locus encodes Drosophila Dystrophin, which acts with other components of the Dystrophin Associated Protein Complex to influence intercellular signalling in developing wing veins. Dev Biol 313: 519-32 PubMed GONUTS page
- ↑ 7.0 7.1 Greener MJ & Roberts RG (2000) Conservation of components of the dystrophin complex in Drosophila. FEBS Lett 482: 13-8 PubMed GONUTS page
- ↑ Sciandra F et al. (2001) Identification of the beta-dystroglycan binding epitope within the C-terminal region of alpha-dystroglycan. Eur J Biochem 268: 4590-7 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Haines N et al. (2007) Dystroglycan and protein O-mannosyltransferases 1 and 2 are required to maintain integrity of Drosophila larval muscles. Mol Biol Cell 18: 4721-30 PubMed GONUTS page
- ↑ Bogdanik L et al. (2008) Muscle dystroglycan organizes the postsynapse and regulates presynaptic neurotransmitter release at the Drosophila neuromuscular junction. PLoS One 3: e2084 PubMed GONUTS page
- ↑ Wairkar YP et al. (2008) Synaptic defects in a Drosophila model of congenital muscular dystrophy. J Neurosci 28: 3781-9 PubMed GONUTS page
