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FB:Dap160
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Dap160 ( synonyms: CG1099, DAP-160, DAP160, Dap160/intersectin, Intersectin, dap160, intersectin, noncoding_4110, p160 ) | |
| Protein Name(s) | Dynamin associated protein 160, | |
| External Links | ||
| FB | FBgn0023388 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002052 |
positive regulation of neuroblast proliferation |
FB:FBrf0207204 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005509 |
calcium ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0207204 |
IPI: Inferred from Physical Interaction |
FB:FBgn0026192 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0207204 |
IPI: Inferred from Physical Interaction |
FB:FBgn0261854 |
F |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0207204 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0210975 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007269 |
neurotransmitter secretion |
FB:FBrf0108281 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008021 |
synaptic vesicle |
FB:FBrf0209874 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0008104 |
protein localization |
FB:FBrf0179283 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008104 |
protein localization |
FB:FBrf0207204 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045179 |
apical cortex |
FB:FBrf0207204 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0184155 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045860 |
positive regulation of protein kinase activity |
FB:FBrf0207204 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0048488 |
synaptic vesicle endocytosis |
FB:FBrf0108281 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048488 |
synaptic vesicle endocytosis |
FB:FBrf0179283 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048488 |
synaptic vesicle endocytosis |
FB:FBrf0179322 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048488 |
synaptic vesicle endocytosis |
FB:FBrf0202144 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051124 |
synaptic growth at neuromuscular junction |
FB:FBrf0179283 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
colocalizes_with |
GO:0042734 |
presynaptic membrane |
FB:FBrf0179322 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Chabu C & Doe CQ (2008) Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression. Development 135: 2739-46 PubMed GONUTS page
- ↑ 2.0 2.1 Stimson DT & Ramaswami M (1999) Vesicle recycling at the Drosophila neuromuscular junction. Int Rev Neurobiol 43: 163-89 PubMed GONUTS page
- ↑ Jiao W et al. (2010) A semi-correlative technique for the subcellular localization of proteins in Drosophila synapses. J Neurosci Methods 185: 273-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Koh TW et al. (2004) Dap160/intersectin acts as a stabilizing scaffold required for synaptic development and vesicle endocytosis. Neuron 43: 193-205 PubMed GONUTS page
- ↑ Tang H et al. (2005) Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway. Mol Cell Biol 25: 2899-909 PubMed GONUTS page
- ↑ 6.0 6.1 Marie B et al. (2004) Dap160/intersectin scaffolds the periactive zone to achieve high-fidelity endocytosis and normal synaptic growth. Neuron 43: 207-19 PubMed GONUTS page
- ↑ Koh TW et al. (2007) Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development. J Cell Biol 178: 309-22 PubMed GONUTS page
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