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FB:DNApol-epsilon

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) DNApol-epsilon ( synonyms: 6768, BAB17608, CG6768, DNApolymarase E, pol-epsilon )
Protein Name(s) DNA polymerase epsilon,
External Links
FB FBgn0020756

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006134
InterPro:IPR006172

F

From FB

GO:0003677

DNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006134

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0091359
PMID:9016770[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:L09561

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0141276
PMID:11579108[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0087794
PMID:8785516[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0006261

DNA-dependent DNA replication

FB:FBrf0091359
PMID:9016770[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0006974

response to DNA damage stimulus

FB:FBrf0208272
PMID:19543366[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR013697

F

From FB

GO:0008296

3'-5'-exodeoxyribonuclease activity

FB:FBrf0091359
PMID:9016770[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0008622

epsilon DNA polymerase complex

FB:FBrf0091359
PMID:9016770[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0008622

epsilon DNA polymerase complex

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

EMBL:L09561

C

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Aoyagi N et al. (1997) DNA polymerase epsilon from Drosophila melanogaster. Biochem Biophys Res Commun 230: 297-301 PubMed GONUTS page
  2. Burgers PM et al. (2001) Eukaryotic DNA polymerases: proposal for a revised nomenclature. J Biol Chem 276: 43487-90 PubMed GONUTS page
  3. Yamaguchi M et al. (1995) Expression patterns of DNA replication enzymes and the regulatory factor DREF during Drosophila development analyzed with specific antibodies. Biol Cell 85: 147-55 PubMed GONUTS page
  4. Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
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