Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:DNApol-alpha180

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) DNApol-alpha180 ( synonyms: 180 kDa subunit, 180 kDa subunit of polymerase-primase, 183 kDa pol alpha, AAB24152, CG6349, DNA Pol-alpha180, DNA pol 180, DNA polalpha, DNA polymerase 180K, DNA polymerase alpha, DNA polymerase alpha 148,000 alpha subunit, DNA polymerase alpha 182,000 alpha subunit, DNA polymerase-primase 180 kda subunit, DNA-Polalpha, DNA-polymerase alpha, DNApol, DNApol-alpha, DNApola, DNApolalpha, DNApolalpha180, DmPolalpha, Dmpol alpha, E(mus304), Enhancer of mus304, POLA, Pol, Pol alpha, Polalpha, pol alpha, polalpha, polalphap180 )
Protein Name(s) DNA polymerase alpha 180kD,
External Links
FB FBgn0259113

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR004578
InterPro:IPR006134
InterPro:IPR006172
InterPro:IPR017964

F

From FB

GO:0001882

nucleoside binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015088

F

From FB

GO:0003677

DNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR004578
InterPro:IPR006134

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0035136
PMID:6773966[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0040120
PMID:6403945[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0057420
PMID:1360647[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P09884

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0123876

NAS: Non-traceable Author Statement

F

From FB

GO:0003887

DNA-directed DNA polymerase activity

FB:FBrf0141276
PMID:11579108[4]

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0056472
PMID:1429896[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005658

alpha DNA polymerase:primase complex

FB:FBrf0035136
PMID:6773966[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005658

alpha DNA polymerase:primase complex

FB:FBrf0040120
PMID:6403945[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005658

alpha DNA polymerase:primase complex

FB:FBrf0057420
PMID:1360647[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005658

alpha DNA polymerase:primase complex

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P09884

C

From FB

GO:0005658

alpha DNA polymerase:primase complex

FB:FBrf0123876

NAS: Non-traceable Author Statement

C

From FB

GO:0006260

DNA replication

FB:FBrf0035136
PMID:6773966[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0006260

DNA replication

FB:FBrf0040120
PMID:6403945[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0006271

DNA strand elongation involved in DNA replication

FB:FBrf0123876

NAS: Non-traceable Author Statement

P

From FB

GO:0008296

3'-5'-exodeoxyribonuclease activity

FB:FBrf0123876

NAS: Non-traceable Author Statement

F

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Villani G et al. (1980) DNA polymerase alpha from Drosophila melanogaster embryos. Subunit structure. J Biol Chem 255: 9479-83 PubMed GONUTS page
  2. 2.0 2.1 2.2 Kaguni LS et al. (1983) Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster. Proc Natl Acad Sci U S A 80: 2221-5 PubMed GONUTS page
  3. 3.0 3.1 Peck VM et al. (1992) Delta-type DNA polymerase characterized from Drosophila melanogaster embryos. Nucleic Acids Res 20: 5779-84 PubMed GONUTS page
  4. Burgers PM et al. (2001) Eukaryotic DNA polymerases: proposal for a revised nomenclature. J Biol Chem 276: 43487-90 PubMed GONUTS page
  5. Melov S et al. (1992) Molecular characterisation of the gene for the 180 kDa subunit of the DNA polymerase-primase of Drosophila melanogaster. J Cell Sci 102 ( Pt 4): 847-56 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox