GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:CycB
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | CycB ( synonyms: 2g, 3510, CG3510, CYCB, Cyc B, Cycb, Cyclin B1, Cyclin-B, CyclinB, DmcycB, cyc B, cyc-B, cycB, cyclin B, cyclinB, dCyclinB, mAbF2F4 ) | |
| Protein Name(s) | Cyclin B, | |
| External Links | ||
| FB | FBgn0000405 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000079 |
regulation of cyclin-dependent protein kinase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0000086 |
G2/M transition of mitotic cell cycle |
FB:FBrf0105828 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0000086 |
G2/M transition of mitotic cell cycle |
FB:FBrf0123735 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0000092 |
mitotic anaphase B |
FB:FBrf0136835 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000281 |
cytokinesis after mitosis |
FB:FBrf0158812 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000775 |
chromosome, centromeric region |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0136835 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0001700 |
embryonic development via the syncytial blastoderm |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005819 |
spindle |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0006974 |
response to DNA damage stimulus |
FB:FBrf0208272 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007079 |
mitotic chromosome movement towards spindle pole |
FB:FBrf0136835 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008608 |
attachment of spindle microtubules to kinetochore |
FB:FBrf0158818 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008608 |
attachment of spindle microtubules to kinetochore |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009987 |
cellular process |
FB:FBrf0175143 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010389 |
regulation of G2/M transition of mitotic cell cycle |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0016538 |
cyclin-dependent protein kinase regulator activity |
FB:FBrf0056454 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0016538 |
cyclin-dependent protein kinase regulator activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0016538 |
cyclin-dependent protein kinase regulator activity |
FB:FBrf0123735 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0019901 |
protein kinase binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0019908 |
nuclear cyclin-dependent protein kinase holoenzyme complex |
FB:FBrf0123735 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0035186 |
syncytial blastoderm mitotic cell cycle |
FB:FBrf0203112 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0015625 |
P |
From FB |
||
| GO:0035561 |
regulation of chromatin binding |
FB:FBrf0207218 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0015270 |
P |
From FB |
||
| GO:0045495 |
pole plasm |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0051233 |
spindle midzone |
FB:FBrf0194687 |
IDA: Inferred from Direct Assay |
C |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Fuller MT (1998) Genetic control of cell proliferation and differentiation in Drosophila spermatogenesis. Semin Cell Dev Biol 9: 433-44 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Parry DH & O'Farrell PH (2001) The schedule of destruction of three mitotic cyclins can dictate the timing of events during exit from mitosis. Curr Biol 11: 671-83 PubMed GONUTS page
- ↑ Echard A & O'Farrell PH (2003) The degradation of two mitotic cyclins contributes to the timing of cytokinesis. Curr Biol 13: 373-83 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
- ↑ Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
- ↑ Parry DH et al. (2003) Cyclin B destruction triggers changes in kinetochore behavior essential for successful anaphase. Curr Biol 13: 647-53 PubMed GONUTS page
- ↑ Boutros M et al. (2004) Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303: 832-5 PubMed GONUTS page
- ↑ Maldonado-Codina G & Glover DM (1992) Cyclins A and B associate with chromatin and the polar regions of spindles, respectively, and do not undergo complete degradation at anaphase in syncytial Drosophila embryos. J Cell Biol 116: 967-76 PubMed GONUTS page
- ↑ McCleland ML & O'Farrell PH (2008) RNAi of mitotic cyclins in Drosophila uncouples the nuclear and centrosome cycle. Curr Biol 18: 245-54 PubMed GONUTS page
- ↑ Baldinger T & Gossen M (2009) Binding of Drosophila ORC proteins to anaphase chromosomes requires cessation of mitotic cyclin-dependent kinase activity. Mol Cell Biol 29: 140-9 PubMed GONUTS page
- ↑ Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
- ↑ Swan A & Schüpbach T (2007) The Cdc20 (Fzy)/Cdh1-related protein, Cort, cooperates with Fzy in cyclin destruction and anaphase progression in meiosis I and II in Drosophila. Development 134: 891-9 PubMed GONUTS page
