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FB:Csk
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | Csk ( synonyms: C-Src kinase, C-terminal-Src kinase, CG17309, CG32852, CG42317, CSK, DCsk, csk, dCSK, dCsk, dcsk, flik, l(3)S017909, l(3)j1D8, lethal (3) S017909, lethal (3) j1D8 ) | |
| Protein Name(s) | C-terminal Src kinase, | |
| External Links | ||
| FB | FBgn0262081 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004672 |
protein kinase activity |
FB:FBrf0126411 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0162272 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0179378 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000719 |
P |
From FB |
||
| GO:0007165 |
signal transduction |
FB:FBrf0126411 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007293 |
germarium-derived egg chamber formation |
FB:FBrf0194413 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008285 |
negative regulation of cell proliferation |
FB:FBrf0126411 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008285 |
negative regulation of cell proliferation |
FB:FBrf0179404 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010669 |
epithelial structure maintenance |
FB:FBrf0190225 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0034334 |
adherens junction maintenance |
FB:FBrf0190225 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043068 |
positive regulation of programmed cell death |
FB:FBrf0190225 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045197 |
establishment or maintenance of epithelial cell apical/basal polarity |
FB:FBrf0190225 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045926 |
negative regulation of growth |
FB:FBrf0162272 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045926 |
negative regulation of growth |
FB:FBrf0179378 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004603 |
P |
From FB |
||
| GO:0045926 |
negative regulation of growth |
FB:FBrf0179378 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0262733 |
P |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 2.0 2.1 Stewart RA et al. (2003) A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila. Oncogene 22: 6436-44 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Pedraza LG et al. (2004) Drosophila Src-family kinases function with Csk to regulate cell proliferation and apoptosis. Oncogene 23: 4754-62 PubMed GONUTS page
- ↑ O'Reilly AM et al. (2006) Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells. Development 133: 2627-38 PubMed GONUTS page
- ↑ Read RD et al. (2004) Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways. Mol Cell Biol 24: 6676-89 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Vidal M et al. (2006) Csk-deficient boundary cells are eliminated from normal Drosophila epithelia by exclusion, migration, and apoptosis. Dev Cell 10: 33-44 PubMed GONUTS page
