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FB:CrebB-17A

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) CrebB-17A ( synonyms: CG6103, CRE-BP, CREB, CREB-B, CREB-b, CREB2, CREB2a, CREB2b, CREBB-17A, Creb, Creb17A, Creb2, Creb2-b, Creb2b, CrebB, CrebB17-A, S162, activator, blocker, cAMP response element-binding protein, cAMP-regulated enhancer-binding protein, cAMP-response element binding protein, cAMP-response element-binding protein, cyclic AMP response element binding protein, dCREB, dCREB-2, dCREB-2a, dCREB-B, dCREB2, dCREB2-a, dCREB2-b, dCREB2a, dCREB2b, dCbz, dCreb2, dCreb2-b, dCrebB2, l(1)17Af, lethal(1)17Af, n )
Protein Name(s) Cyclic-AMP response element binding protein B at 17A,
External Links
FB FBgn0014467

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

FB:FBrf0083527
PMID:7651429[1]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0003677

DNA binding

FB:FBrf0122287

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001630
InterPro:IPR004827
InterPro:IPR011616

F

From FB

GO:0005634

nucleus

FB:FBrf0083527
PMID:7651429[1]

IMP: Inferred from Mutant Phenotype

C

From FB

GO:0005634

nucleus

FB:FBrf0122287

NAS: Non-traceable Author Statement

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0083527
PMID:7651429[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007611

learning or memory

FB:FBrf0141665
PMID:11715043[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0007616

long-term memory

FB:FBrf0167276
PMID:14515157[3]

TAS: Traceable Author Statement

P

From FB

GO:0007616

long-term memory

FB:FBrf0180428
PMID:15470148[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007616

long-term memory

FB:FBrf0194016
PMID:17145505[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0007622

rhythmic behavior

FB:FBrf0151232
PMID:12111533[6]

TAS: Traceable Author Statement

P

From FB

GO:0007622

rhythmic behavior

FB:FBrf0155881
PMID:12486701[7]

TAS: Traceable Author Statement

P

From FB

GO:0007623

circadian rhythm

FB:FBrf0159046
PMID:12486704[8]

TAS: Traceable Author Statement

P

From FB

GO:0007623

circadian rhythm

FB:FBrf0159070
PMID:12626480[9]

TAS: Traceable Author Statement

P

From FB

GO:0030431

sleep

FB:FBrf0139772
PMID:11687816[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0209175
PMID:14507783[11]

IDA: Inferred from Direct Assay

F

From FB

GO:0045187

regulation of circadian sleep/wake cycle, sleep

FB:FBrf0159046
PMID:12486704[8]

TAS: Traceable Author Statement

P

From FB

GO:0045187

regulation of circadian sleep/wake cycle, sleep

FB:FBrf0159070
PMID:12626480[9]

TAS: Traceable Author Statement

P

From FB

GO:0045475

locomotor rhythm

FB:FBrf0141665
PMID:11715043[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0209175
PMID:14507783[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046983

protein dimerization activity

FB:FBrf0152056
PMID:12176927[12]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0046983

protein dimerization activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR011616

F

From FB

GO:0072375

medium-term memory

FB:FBrf0187900
PMID:16135747[13]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Yin JC et al. (1995) A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. Mol Cell Biol 15: 5123-30 PubMed GONUTS page
  2. 2.0 2.1 Sokolowski MB (2001) Drosophila: genetics meets behaviour. Nat Rev Genet 2: 879-90 PubMed GONUTS page
  3. Korzus E (2003) The relation of transcription to memory formation. Acta Biochim Pol 50: 775-82 PubMed GONUTS page
  4. Perazzona B et al. (2004) The role of cAMP response element-binding protein in Drosophila long-term memory. J Neurosci 24: 8823-8 PubMed GONUTS page
  5. Yu D et al. (2006) Drosophila alpha/beta mushroom body neurons form a branch-specific, long-term cellular memory trace after spaced olfactory conditioning. Neuron 52: 845-55 PubMed GONUTS page
  6. Stanewsky R (2002) Clock mechanisms in Drosophila. Cell Tissue Res 309: 11-26 PubMed GONUTS page
  7. Stanewsky R (2003) Genetic analysis of the circadian system in Drosophila melanogaster and mammals. J Neurobiol 54: 111-47 PubMed GONUTS page
  8. 8.0 8.1 Shaw PJ & Franken P (2003) Perchance to dream: solving the mystery of sleep through genetic analysis. J Neurobiol 54: 179-202 PubMed GONUTS page
  9. 9.0 9.1 Hendricks JC (2003) Invited review: Sleeping flies don't lie: the use of Drosophila melanogaster to study sleep and circadian rhythms. J Appl Physiol 94: 1660-72; discussion 1673 PubMed GONUTS page
  10. Hendricks JC et al. (2001) A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis. Nat Neurosci 4: 1108-15 PubMed GONUTS page
  11. 11.0 11.1 Grienenberger A et al. (2003) Tgfbeta signaling acts on a Hox response element to confer specificity and diversity to Hox protein function. Development 130: 5445-55 PubMed GONUTS page
  12. Fassler J et al. (2002) B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partners. Genome Res 12: 1190-200 PubMed GONUTS page
  13. Honjo K & Furukubo-Tokunaga K (2005) Induction of cAMP response element-binding protein-dependent medium-term memory by appetitive gustatory reinforcement in Drosophila larvae. J Neurosci 25: 7905-13 PubMed GONUTS page
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